Compound acetaminophen tablets (Ⅱ)
Function and Efficacy
The acetaminophen and isopropyl antipyrine in this product can inhibit the synthesis of prostaglandins and have antipyretic and analgesic effects: anhydrous caffeine is a central nervous system stimulant and can enhance the antipyretic and analgesic effects of the first two. This product is mainly rapidly absorbed through the gastrointestinal tract, with the plasma peak of acetaminophen appearing within 30-120 minutes and a half-life of 3-4 hours. It is mainly metabolized by the liver into glucuronic acid and sulfate compounds and excreted through the kidneys. The plasma peak of isopropyl antipyrine appears within 15-30 minutes and a half-life of 1-3 hours. It is also mainly metabolized by the liver and excreted through the kidneys.
Ingredients
Acetaminophen 250 mg, isopropyl antipyrine 150 mg, anhydrous caffeine 50 mg. Excipients: microcrystalline cellulose, hypromellose, formaldehyde casein, corn starch, magnesium stearate, talc, micro powder silica gel.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| AcetaminophenIngredients |
Inhibits prostaglandin synthesis and has antipyretic and analgesic effects More |
103-90-2 | 68 | |
| PropyphenazoneIngredients |
Inhibits prostaglandin synthesis and has antipyretic and analgesic effects More |
479-92-5 | 5 |
Appearance
This product is white tablets.
Indication
It is used to treat fever caused by the common cold or influenza, and is also used to relieve mild to moderate pain such as headache, joint pain, migraine, toothache, muscle pain, neuralgia, and dysmenorrhea.
Usage and Dosage
Oral administration: Children over 6 years old take 0.5-1 tablet at a time; Adults take 1-2 tablets at a time, 3 times a day.
Adverse Reactions
Leukocytosis, methemoglobinemia and thrombocytopenia, as well as other allergic reactions such as anorexia, nausea, vomiting, and rash are occasionally seen.
Precautions
It is contraindicated in patients with a history of hemolytic anemia or severe liver or kidney dysfunction.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.
Drug Interactions
1. Patients who use barbiturates (such as phenbital) or antispasmodics (such as belladonna) may suffer liver damage if they use this product for a long time, so they should not be taken together. 2. This product can enhance the toxicity of chloramphenicol when used together, so they should not be taken together. 3. If used together with other drugs, drug interactions may occur. Please consult a physician or pharmacist for details.
Storage
Keep sealed.
Packaging Specification
Acetaminophen 0.25g, isopropyl antipyrine 0.15g, anhydrous caffeine 50mg
Validity Period
24 months
Manufacturer
Chongqing KERUI Pharmaceutical (GROUP) Co., Ltd.
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Founded in:
1999-03-03 -
Address:
No. 2 Dashizhi Road, Nan'an Economic and Technological Development Zone, Chongqing -
Tax NO.:
915001082031636780 -
Registered Funds:
110.6375 million yuan -
Website:
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Email: