Levofloxacin Lactate Sodium Chloride Injection

This product is the levorotatory form of ofloxacin, and its antibacterial activity is about 2 times that of ofloxacin. Its main mechanism of action is to inhibit bacterial DNA gyrase activity and inhibit bacterial DNA replication. It has the characteristics of broad antibacterial spectrum and strong antibacterial effect. It has strong antibacterial activity against most Enterobacteriaceae, such as Klebsiella pneumoniae, Proteus, Salmonella typhi, Shigella, influenza bacillus, some Escherichia coli, Pseudomonas aeruginosa, gonococci, etc. It also has good antibacterial effect against some Staphylococci, Streptococcus pneumoniae, Chlamydia, etc.

The main ingredient of this product is levofloxacin lactate, and its chemical name is: (-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3,-de]-[1,4]benzoxazine-6-carboxylic acid lactate hemihydrate.

Pale yellow-green clear liquid.

It is suitable for moderate to severe respiratory system, urinary system, digestive system and skin and soft tissue infections caused by sensitive strains of Gram-negative bacteria and Gram-positive bacteria, sepsis, typhoid and paratyphoid dysentery, and urethritis and cervicitis caused by gonococci and Chlamydia trachomatis.

Intravenous drip: Adults: 0.1-0.2g at a time, twice a day, or as directed by a doctor.

Poor appetite, nausea, vomiting, diarrhea, insomnia, dizziness, headache, rash, elevated serum alanine aminotransferase and local irritation symptoms after injection may occur occasionally, but they are generally tolerated and disappear after the treatment.

It is contraindicated for patients who are allergic to quinolones and those with epilepsy.

Precautions for children: In animal experiments (puppies, young adult dogs, and young mice), it was found that this product caused abnormal damage to weight-bearing joints, so it is contraindicated for patients under 18 years old. Precautions for pregnancy and lactation: 1. Because the safety of the drug for pregnant women cannot be ensured, it is contraindicated for pregnant women or women who may become pregnant. 2. Because the drug is excreted through breast milk, it is contraindicated for lactating women. If you must take this drug, you should stop breastfeeding. Precautions for the elderly: This product is mainly excreted through the kidneys (see "Pharmacokinetics"), because most elderly patients have low renal function, they may have persistently high blood drug concentrations. Therefore, you should pay attention to the dosage and administer the drug with caution.

1. This product cannot be used in the same infusion tube with solutions of polyvalent metal ions such as magnesium and calcium. 2. This product may cause convulsions when used in combination with phenylpropionic acid, fentanyl, and non-steroidal anti-inflammatory analgesics, so its combination should be avoided. 3. Avoid using it simultaneously with theophylline. If it is necessary to use it simultaneously, the blood concentration of theophylline should be monitored to adjust its dosage. 4. When used simultaneously with warfarin or its derivatives, the prothrombin time or other coagulation tests should be monitored. 5. When used simultaneously with oral hypoglycemic drugs, it may cause hypoglycemia. Therefore, attention should be paid to monitoring blood sugar concentration during medication. Once hypoglycemia occurs, this product should be discontinued immediately and appropriate treatment should be given.

Keep in a dark, airtight, cool place.

100ml:0.1g (based on levofloxacin)

24 months

Henan Shuanghe Huali Pharmaceutical Co., Ltd.

• Founded in:

  2011-09-30

• Address:

  No. 369 Qinggong Road, Pingdingshan City

• Tax NO.:

  91410400582895296J

• Registered Funds:

  118 million yuan

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