Cyclosporine oral solution

The main ingredient of this product is cyclosporine. Molecular weight: C62H111N11O12

This product is a light yellow or yellow clear oily liquid.

Oral administration: Take 15 mg/kg daily starting 4-12 hours before transplantation. Reduce the dose by 2 mg/kg daily 1-2 weeks after surgery to a maintenance dose of 6-8 mg/kg daily.

1. Common adverse reactions include tremor, anorexia, nausea, vomiting, etc. 2. The most common side effects are hirsutism, tremor, gastrointestinal discomfort, gingival hyperplasia, and liver and kidney toxicity. Fatigue, anorexia, paresthesia of the limbs, hypertension, amenorrhea, and convulsions can also be seen.

1. Those who are allergic to cyclosporine. 2. Those with severe liver or kidney damage, uncontrolled hypertension, infection or malignant tumors should not use or use with caution.

Precautions for children: There is limited data on the use of this product in children, so no recommendation is made for non-transplant patients under 16 years of age, except for nephrotic syndrome. Precautions for pregnancy and lactation: Animal reproduction studies have shown that this product has no teratogenic effect. However, there is still a lack of controlled trials for clinical use in pregnant women. Data from existing organ transplant recipients show that compared with traditional treatments, this product does not increase the risk of side effects in patients' pregnancy and delivery, but there is still a lack of sufficient and complete controlled studies on pregnant women. Therefore, pregnant women can only receive this product when the efficacy of the drug clearly exceeds its potential risk to the fetus. Cyclosporine can be secreted in breast milk, so mothers taking this product should not breastfeed. Precautions for the elderly: Not yet clear.

1. The combined use of nepsilon with estrogen, androgen, cimetidine, diltiazem, erythromycin, ketoconazole, etc. can increase the plasma concentration of nepsilon. Therefore, the liver and kidney toxicity of nepsilon may be increased. Therefore, caution should be exercised when used in combination with the above-mentioned drugs, and the patient's liver and kidney function and the blood concentration of nepsilon should be monitored. 2. When used in combination with non-steroidal anti-inflammatory analgesics such as indomethacin, the risk of renal failure may be increased. 3. When using nepsilon, such as transfusing stored blood that has been stored for more than 10 days or combining nepsilon with potassium-sparing diuretics, high potassium-containing drugs, etc., the blood potassium level may increase. 4. Used in combination with liver enzyme inducers: Because it will induce liver microsomal enzymes, it will increase the metabolism of nepsilon. Therefore, the dose of nepsilon must be adjusted. 5. Used with adrenocortical hormones, azathioprine, chlorambucil

seal.

30mg:3g

24 months

Sinopharm ChuanKang Pharmaceutical Co., Ltd.

• Founded in:

  2003-05-09

• Address:

  No. 2, Xinwen Road, West Park, Chengdu Hi-tech Zone

• Tax NO.:

  91510100749702784T

• Registered Funds:

  40 million yuan

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