Penciclovir cream

This product is a nucleoside antiviral drug, which has an inhibitory effect on type I and type II herpes simplex viruses in vitro. In virus-infected cells, viral thymidine deoxynucleoside kinase phosphorylates this product into penciclovir monophosphate, and then cellular kinase converts penciclovir monophosphate into penciclovir triphosphate. In vitro experiments have shown that penciclovir triphosphate and deoxyguanosine triphosphate competitively inhibit herpes simplex virus polymerase, thereby selectively inhibiting the synthesis and inhibition of herpes simplex virus DNA. The generation of herpes simplex virus mutants resistant to this product is due to changes in the properties of viral thymidine deoxynucleoside kinase or DNA polymerase. The most common acyclovir-resistant virus mutants lack thymidine kinase, and they are also resistant to this product.

The main ingredient of this product is: Penciclovir. Its chemical name is: 9-[4-hydroxy-3-(hydroxymethyl)-butyl]-guanine.

This product is a white or off-white cream.

Herpes simplex on the lips or face, genital herpes.

For external use: Apply to the affected area 4 to 5 times a day. Treatment should be started as soon as possible (if any signs or damage occur).

No systemic adverse reactions were observed, but local burning sensation, pain, and itching were occasionally observed.

It is contraindicated for those who are allergic to this product.

Precautions for children: Children should use under the guidance of a doctor. Precautions for pregnancy and lactation: Pregnant and lactating women should use under the guidance of a doctor. Precautions for the elderly: Not yet clear.

Not yet clear.

Keep sealed in a cool place (not exceeding 20°C).

10g:0.1g

24 months.

Shanghaizhaohui Pharmaceutical Co., Ltd.

• Founded in:

  1988-03-23

• Address:

  No. 2151, Fuyuan Road, Baoshan District, Shanghai

• Tax NO.:

  913101131332324468

• Registered Funds:

  100 million yuan

• Website:

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