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Terfenadine Tablets

Function and Efficacy

This product is a specific H1 receptor blocker. At an effective antihistamine dose, this product and its metabolites are not easy to pass through the blood-brain barrier, so they rarely have central nervous system inhibitory effects.

Ingredients

The main ingredients of this product and its chemical name are: Terfenadine. Its chemical name is a-[4-(1,1-dimethylethyl)phenyl]-4-(hydroxy-diphenylmethyl)-1-piperidinol. Molecular formula: C32H41NO2. Molecular weight: 471.69

Name Description Content CAS NO. Manufacturer
TerfenadineIngredients

This product is a specific H1 receptor blocker. At an effective antihistamine dose, this product and its metabolites are not easy to pass through the blood-brain barrier, so they rarely have central nervous system inhibitory effects.

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50679-08-8 18

Appearance

This product is white or off-white tablets.

Indication

For the treatment of seasonal and non-seasonal allergic rhinitis, urticaria and hay fever.

Usage and Dosage

Oral administration. Adults and those over 12 years old: 60 mg once, twice a day; Children aged 6-12 years old: 30 mg once, twice a day, or as directed by a doctor.

Adverse Reactions

1. Cardiovascular system: According to foreign literature reports, the following adverse reactions are rare, such as ventricular arrhythmia, torsades de pointes, ventricular tachycardia, ventricular fibrillation, cardiac arrest, hypotension, atrial flutter, syncope, dizziness, QTc interval prolongation, etc. Most of the above reactions are caused by drug interactions; 2. Central nervous system: such as headache, dizziness, fatigue, etc.; 3. Gastrointestinal system: such as abdominal discomfort, nausea, vomiting, increased appetite, changes in bowel habits, etc.; 4. Others: such as dry mouth, dry nose, dry throat, rash, etc.

Precautions

1. It is contraindicated to be used in combination with certain azole antifungal drugs (such as ketoconazole, itraconazole, etc.), certain macrolide antibiotics (such as erythromycin, clarithromycin, oleandomycin, etc.) and other drugs that seriously damage liver function; 2. It is contraindicated in patients with obvious liver damage; 3. It is contraindicated in patients with organic heart disease, especially those with atrioventricular block and congenital QTc interval prolongation syndrome (Romano-Ward Syndrome); 4. It is contraindicated to take in excess; 5. It is contraindicated in patients who are allergic to this product.

Special Population Medication

Precautions for children: Suitable for children over 6 years old. Precautions for pregnancy and lactation: Use with caution for pregnant and lactating women. Precautions for the elderly: Use with caution.

Drug Interactions

It is contraindicated to be used in combination with triazole antifungal drugs (such as ketoconazole, itraconazole, etc.), certain macrolide antibiotics (such as clarithromycin, erythromycin, oleandomycin, etc.) and other drugs that seriously damage liver function.

Storage

Sealed, store in a cool, dry place.

Packaging Specification

60mg

Validity Period

36 months

Manufacturer

Jiangsu Hengrui Pharmaceuticals Co., Ltd.

  • Founded in:

    1997-04-28
  • Address:

    No. 38 Huanghe Road, Lianyungang Economic and Technological Development Zone
  • Tax NO.:

    9132070070404786XB
  • Registered Funds:

    6,379,002,274 yuan
  • Website:

  • Email:

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