Ammonium Ferric Citrate Effervescent Granules
Function and Efficacy
This preparation enhances the proton signal in water when in aqueous solution, which shows that it is effective as an oral contrast agent for magnetic resonance imaging. The results of rat experiments showed that the contrast effect of the gastrointestinal tract was enhanced after administration of a certain amount of ammonium ferric citrate solution (1-3mmol/L), and the gastrointestinal cavity could be identified from the adjacent soft tissue. Rabbit experiments showed that ammonium ferric citrate (2mmol/L) achieved satisfactory enhancement of the signal contrast on the T1W and T2W images of the spin echo (SE) sequence. Referring to foreign literature, the results of acute toxicity experiments showed that when the maximum dose of a single oral administration of ammonium ferric citrate effervescent powder to rats and dogs was 2000mg/kg, no obvious toxic reactions were observed except for changes in feces (such as softened or watery stools). A single intraperitoneal injection of 120mg/kg of ammonium ferric citrate effervescent powder in rats
Ingredients
Ammonium Ferric Citrate
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Ammonium ferric citrateIngredients |
This preparation enhances the proton signal in water in aqueous solution, which shows that it is effective as an oral contrast agent for magnetic resonance imaging. The results of rat experiments show that the contrast effect of the gastrointestinal tract is enhanced after a certain amount of ammonium ferric citrate solution (1-3mmol/L) is given, and the gastrointestinal cavity can be identified from the adjacent soft tissue. Rabbit experiments show that ammonium ferric citrate (2mmol/L) can satisfactorily enhance the signal contrast on the T1W and T2W images of the spin echo (SE) sequence. Referring to foreign literature, the results of acute toxicity experiments show that when the maximum dose of ammonium ferric citrate effervescent powder is 2000mg/kg for rats and dogs, no obvious toxic reactions are observed except for fecal changes (such as softened or watery stools). More |
1185-57-5 | 3 |
Appearance
This product is brown granules.
Indication
Used for magnetic resonance abdominal imaging to perform contrast imaging of the digestive tract (stomach, duodenum and jejunum).
Usage and Dosage
The adult dosage is 1 bag, dissolved in 300ml of water, taken orally. If necessary, 2 bags can be taken orally, dissolved in the same amount of water. Magnetic resonance imaging is usually performed within 20 minutes after taking the medicine.
Adverse Reactions
According to foreign clinical data, 0.1-0.5% of patients experience diarrhea; 0.1% experience nausea, vomiting, and decreased appetite; a very small number of patients experience stomach discomfort and abdominal distension. All of the above symptoms can disappear on their own.
Precautions
1; Patients with iron overload 2; Patients with iron allergy 3; Patients with or suspected complete intestinal obstruction or intestinal perforation.
Drug Interactions
No relevant reports have been seen yet.
Storage
Keep in a light-proof, sealed, dry place. Tentatively two years.
Packaging Specification
6g:1.2g (equivalent to 258mg of iron)
Manufacturer
Beijing Beilu Pharmaceutical Co., Ltd.
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Founded in:
1992-09-05 -
Address:
No. 3, Shuiyuan West Road, Miyun District, Beijing -
Tax NO.:
91110000102017145R -
Registered Funds:
491.855896 yuan -
Website:
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Email: