Ipriflavone tablets

According to literature reports, this product is a plant-based bone formation-promoting drug that can directly act on bones and has estrogen-like anti-osteoporosis properties, but without the effects of estrogen on the reproductive system. Its anti-osteoporosis mechanism is: 1. Promote the proliferation of osteoblasts, promote the synthesis of bone collagen and the mineralization of bone matrix, and increase bone mass; 2. Reduce the proliferation and differentiation of osteoclast precursor cells, inhibit the activity of mature osteoclasts, and reduce bone absorption; 3. Increase the secretion of calcitonin through estrogen-like effects, and indirectly produce anti-bone absorption effects. The acute toxicity of this product is very small. The LD50 for oral administration to mice is 10000mg/kg, and the LD50 for intraperitoneal injection is 2500mg/kg. The long-term toxicity of oral administration to dogs for one year is

Ipriflavone

This product is white or off-white tablets.

It is suitable for improving the symptoms of primary osteoporosis and increasing the bone density of those with osteopenia.

Take orally after meals. Three times a day, 0.2g (1 tablet) each time, or as directed by a doctor.

Rare: The incidence of adverse reactions is less than 0.1%; Occasionally: Less than 0.1-5%; Common: More than 5%. (1) Important adverse reactions: 1) Peptic ulcer, gastrointestinal bleeding: Peptic ulcer, gastrointestinal bleeding or worsening symptoms are rare. When this happens, the drug should be discontinued immediately and appropriate treatment should be given. Therefore, patients with peptic ulcers or a history of peptic ulcers should use it with caution. 2) Jaundice: Jaundice is rare, so it should be closely observed. If there is any abnormality, stop using the drug immediately and take appropriate treatment. (2) Other adverse reactions: 1) Allergic reaction: Symptoms such as rash and itching are occasionally seen, and the drug should be discontinued at this time. 2) Digestive organs: Occasionally nausea, vomiting, loss of appetite, stomach discomfort, heartburn, abdominal pain, abdominal distension, diarrhea, constipation, stomatitis, dry mouth, glossitis, abnormal taste, etc. 3) Nervous system: Occasionally dizziness, mild dizziness, rarely headache, etc. 4) Blood: Rarely granulocytopenia, occasionally anemia, etc. 5) Liver: Occasionally, bilirubin GOT, GPT, ALP, LDH increased, rarely, Y-GTP increased. 6) Kidney: Rarely, urea nitrogen and creatinine increased. 7) Others: Rarely, gynecomastia in men, if this occurs, the drug should be stopped. Rarely, tongue and lip numbness, occasionally, edema, discomfort.

1. Patients who are allergic to this product are prohibited from using it. 2. Patients with hypocalcemia are prohibited from using it.

Precautions for children: The safety of the drug for newborns, infants and children has not been determined, so they should not take this drug. Precautions for pregnancy and lactation: The safety of the drug for pregnant and lactating women has not been determined, so they should not take this drug. Precautions for the elderly: Elderly patients should use the drug with caution.

When this product is used in combination with estrogen, theophylline and coumarin anticoagulants, their effects will be enhanced and should be used with caution.

Store in sealed container at room temperature. Keep away from moisture after opening. The validity period is tentatively set at two years.

0.2g

24 months

Hubei Sihuan Pharmaceutical Co., Ltd.

• Founded in:

  2002-09-02

• Address:

  Room C6321, Building C6, No. 666 Gaoxin Avenue, East Lake New Technology Development Zone, Wuhan City, Hubei Province

• Tax NO.:

  914200007417627664

• Registered Funds:

  45 million yuan

• Website:

  Log in to view

• Email:

  Log in to view