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Ethinyl Estradiol Compound Tablets

Function and Efficacy

This product is a compound preparation composed of progesterone and estrogen derivatives. The progesterone derivatives norethindrone and megestrol acetate can prevent the implantation of the fertilized egg and increase the consistency of cervical mucus to prevent sperm penetration. The estrogen derivative ethinyl estradiol can inhibit the secretion of gonadotropin. The three ingredients are combined to inhibit ovarian ovulation and enhance the contraceptive effect.

Ingredients

This product is a compound preparation, each tablet containing 0.3 mg of norethindrone, 0.5 mg of megestrol acetate, and 0.035 mg of ethinyl estradiol.

Name Description Content CAS NO. Manufacturer
NorethindroneIngredients

Prevents the fertilized egg from implanting, increases the thickness of the cervical mucus, and prevents sperm from penetrating

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68-22-4 18
Megestrol acetateIngredients

Prevents the fertilized egg from implanting, increases the thickness of the cervical mucus, and prevents sperm from penetrating

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595-33-5 18
Ethinyl EstradiolIngredients

Inhibit the secretion of gonadotropin, inhibit ovarian ovulation, and enhance contraceptive effect

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57-63-6 21

Appearance

This product is a blue film-coated tablet, which appears white after removing the coating.

Indication

It is suitable for healthy women of childbearing age who require contraception and have no contraindications to the use of steroidal contraceptives.

Usage and Dosage

Oral administration, starting from the 5th day of each menstruation, 1 tablet a day, for 22 consecutive days. Menstruation will occur within 3-7 days after stopping the medication, and the next cycle of medication will be taken on the 5th day of menstruation. Take the medication again after menstruation after childbirth or miscarriage. Taking the medication for one month can prevent pregnancy for one month, so it is necessary to take the medication every month. It is usually taken before bedtime to reduce adverse reactions.

Adverse Reactions

1. Pregnancy-like reactions: nausea, vomiting, drowsiness, dizziness, loss of appetite, etc. 2. Breakthrough bleeding (mostly occurs when a dose is missed, if necessary, 0.005-0.01 mg of ethinyl estradiol can be taken every night), amenorrhea. 3. Mental depression, headache, fatigue, weight gain, facial pigmentation. 4. Liver damage, or increase the relative risk of benign liver adenoma. 5. Women who smoke over 35 years old increase the risk of ischemic heart disease when taking this product. 6. May cause high blood pressure.

Precautions

1. Cardiovascular disease and hypertension; 2. Diabetes; 3. Asthma; 4. Epilepsy; 5. Migraine; 6. Undiagnosed vaginal bleeding; 7. History of thrombosis (except for treatment of advanced cancer); 8. Gallbladder disease; 9. Patients with severe liver and kidney dysfunction and breast lumps are prohibited from using this product; 10. Patients with swelling and pain related to estrogen, such as breast cancer, cervical cancer (except prostate cancer and postmenopausal breast cancer), thrombophlebitis, and pulmonary embolism are prohibited from using this product.

Special Population Medication

Precautions for children: follow doctor's advice. Precautions for pregnancy and lactation: The safety of this product for pregnant women has not been determined. Pregnant women should consider the pros and cons of using this product. Precautions for the elderly: follow doctor's advice.

Drug Interactions

1. Drugs that can reduce the contraceptive effect: Antibacterial drugs, especially oral broad-spectrum antibiotics; Drug enzyme inducers, such as rifampicin, phenobarbital, phenytoin, etc., should be avoided at the same time. 2. This product affects the efficacy of other drugs, and weakens the effects of antihypertensive drugs, anticoagulants and hypoglycemic drugs. It enhances the efficacy of tricyclic antidepressants. 3. If you are taking other drugs, please consult a doctor or pharmacist before using this product.

Storage

Keep away from light and store in sealed container.

Packaging Specification

Norethindrone 0.3 mg, megestrol acetate 0.5 mg, ethinyl estradiol 0.035 mg

Validity Period

36 months.

Manufacturer

Shanghai Sine Tianping Pharmaceutical Co., Ltd.

  • Founded in:

    1998-05-07
  • Address:

    No. 4598, Jindu Road, Minhang District, Shanghai
  • Tax NO.:

    91310112832231856K
  • Registered Funds:

    154.7 million yuan
  • Email:

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