Levofloxacin Hydrochloride Eye Drops

Levofloxacin is the levorotatory form of ofloxacin, and its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit the activity of bacterial topoisomerase IV and DNA gyrase (both are type II topoisomerases), hindering the replication of bacterial DNA to achieve antibacterial effects. Levofloxacin has the characteristics of a broad antibacterial spectrum and strong antibacterial effect. It has strong antibacterial activity against most Enterobacteriaceae, such as Escherichia coli, Klebsiella, Serratia, Proteus, Shigella, Salmonella, Citrobacter, Acinetobacter, and Gram-negative bacteria such as Pseudomonas aeruginosa, Haemophilus influenzae, and Neisseria gonorrhoeae. It also has good antibacterial effects on some methicillin-sensitive Staphylococci, Streptococcus pneumoniae, Streptococcus pyogenes, hemolytic Streptococci, and Legionella, Mycoplasma, and Chlamydia, but has poor effects on anaerobic bacteria and enterococci.

Levofloxacin hydrochloride. Chemical name: (S)-(-)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyridinyl[1,2,3-de]-[1,4]-benzoxazine-6-carboxylic acid hydrochloride monohydrate

This product is a light yellow clear liquid.

This product is suitable for the treatment of bacterial conjunctivitis and bacterial keratitis caused by sensitive bacteria.

Drop the product into the conjunctival sac of the affected eye. 3-5 times a day, 1-2 drops each time. Recommended course of treatment: 7 days for bacterial conjunctivitis, 10-14 days for bacterial keratitis. Or follow the doctor's advice.

The most commonly reported adverse reactions are temporary decreased vision, fever, headache, temporary eye heat, eye pain or discomfort, pharyngitis and photophobia, with an incidence of about 1%-3%. Other adverse reactions with an incidence of less than 1% include: allergy, eyelid edema, dry eyes and itching.

Patients who are allergic to levofloxacin hydrochloride or other quinolones or any components of this product are contraindicated.

Precautions for children: The efficacy and safety of this product for infants under 1 year old have not been established. Oral administration of quinolones to immature animals can cause arthritis, but there is no evidence that levofloxacin eye drops have any effect on weight-bearing joints. Precautions for pregnancy and lactation: Since there are no adequate controlled studies on pregnant women, this product can only be used by pregnant women when it is judged that the potential benefits of the drug outweigh the potential risks to the fetus. Since ofloxacin can be excreted through breast milk, it should be used with caution by lactating women. Precautions for the elderly: There is no overall difference in the efficacy and safety of this product for the elderly and other adult patients.

There is still a lack of information on drug interactions with this product. However, it has been shown that some quinolones can increase the blood concentration of theophylline when administered systemically, interfere with the metabolism of caffeine, and increase the effects of oral anticoagulants such as warfarin and its derivatives. If cyclosporine is taken at the same time, patients may experience a transient increase in serum creatinine.

Keep in a light-proof and airtight container.

5ml:15mg

24 months

Yabang Pharmaceutical Co., Ltd.

• Founded in:

  2010-07-22

• Address:

  No. 66, Changhong West Road, Wujin Economic Development Zone, Changzhou

• Tax NO.:

  91320400559287372K

• Registered Funds:

  300 million yuan

• Email:

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