On ECHEMI
Home > Drugs > Tolvaptan Tablets

Tolvaptan Tablets

Function and Efficacy

A vasopressin V2 receptor antagonist (non-peptide AVP2 receptor antagonist) that can increase the sodium ion concentration in plasma and help excess water be excreted from the urine. Enhance the kidney's ability to process water. Cyclic adenosine monophosphate (cAMP) accumulates in polycystic kidney cells, which promotes cyst growth by stimulating cyst fluid secretion and lining cell proliferation. Tolvaptan is a type 2 vasopressin receptor antagonist that inhibits cAMP generation and accumulation. In a variety of PKD animal model studies, tolvaptan has shown good efficacy.

Ingredients

Molecular weight: C26H25ClN2O3

Name Description Content CAS NO. Manufacturer
TolvaptanIngredients

A vasopressin V2 receptor antagonist (non-peptide AVP2 receptor antagonist) that can increase the sodium ion concentration in plasma and help excess water be excreted from the urine. Enhance the kidney's ability to process water. Cyclic adenosine monophosphate (cAMP) accumulates in polycystic kidney cells, which promotes cyst growth by stimulating cyst fluid secretion and lining cell proliferation. Tolvaptan is a type 2 vasopressin receptor antagonist that inhibits cAMP generation and accumulation. In a variety of PKD animal model studies, tolvaptan has shown good efficacy.

More
150683-30-0 23

Appearance

This product is a blue triangular tablet.

Indication

Treatment of hyponatremia caused by congestive heart failure, cirrhosis, and syndrome of inadequate antidiuretic hormone secretion.

Usage and Dosage

Oral administration, 15 mg/tablet (1 tablet), once a day. Or as directed by a physician.

Adverse Reactions

Dry mouth, thirst, dizziness, nausea, low blood pressure, etc.

Precautions

It is contraindicated for those who are allergic to this product.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Drug Interactions

Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.

Storage

seal.

Packaging Specification

30mg

Validity Period

24 months

Manufacturer

ZheJiang Otsuka Pharmaceutical Co., Ltd.

  • Founded in:

    1991-10-12
  • Address:

    No. 1 Shangguafan, Jinnan Street, Lin'an District, Hangzhou City, Zhejiang Province
  • Tax NO.:

    91330100609129453D
  • Registered Funds:

    $54,333,333
  • Email:

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.