Felbinac gel
Function and Efficacy
This product is a non-steroidal anti-inflammatory drug and an active metabolite of fenbufen. In vitro tests show that the inhibitory effect of this product on prostaglandin synthase cyclooxygenase (guinea pig lung prompt) is equivalent to 1/2 of indomethacin and 10 times of aspirin. Animal experiments show that the drug can be absorbed through the skin and inhibit rat foot swelling induced by carrageenan and rat ear swelling induced by croton oil, increase the pain threshold of carrageenan-induced rat inflammatory foot, and has a local anti-inflammatory effect. Toxicological study: Reproductive toxicity: Subcutaneous injection of 5mg/kg of felbinac in rats from 13 days before mating to the end of the experiment in male rats and 14 days before mating to 7 days of pregnancy in female rats has no effect on the estrus cycle of female rats, the mating rate and conception rate of male and female animals, and the fetus.
Ingredients
The main ingredient of this product is felbinac, and the auxiliary materials are carbomer, diisopropanolamine and ethanol.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| 4-Biphenylacetic acidIngredients |
This product is a non-steroidal anti-inflammatory drug and an active metabolite of fenbufen. Its inhibitory effect on prostaglandin synthase cyclooxygenase is equivalent to 1/2 of indomethacin and 10 times of aspirin. It has a local anti-inflammatory effect, can inhibit carrageenan-induced rat foot swelling and croton oil-induced rat ear swelling, and increase the pain threshold of carrageenan-induced rat inflammatory foot. More |
5728-52-9 | 4 |
Appearance
This product is a water-soluble, colorless, transparent, thick liquid.
Indication
This product is a non-steroidal anti-inflammatory analgesic, mainly used to relieve swelling and pain symptoms caused by osteoarthritis and acute closed soft tissue injuries.
Usage and Dosage
Take 1g each time, 2-4 times a day. If there are multiple injuries, the total amount per day should not exceed 25g (equivalent to 25 times).
Adverse Reactions
This product is a non-steroidal anti-inflammatory drug and an active metabolite of fenbufen. In vitro tests show that the inhibitory effect of this product on prostaglandin synthase cyclooxygenase (guinea pig lung prompt) is equivalent to 1/2 of indomethacin and 10 times of aspirin. Animal experiments show that the drug can be absorbed through the skin and inhibit rat foot swelling induced by carrageenan and rat ear swelling induced by croton oil, increase the pain threshold of carrageenan-induced rat inflammatory foot, and has a local anti-inflammatory effect. Toxicological study: Reproductive toxicity: Subcutaneous injection of 5mg/kg of felbinac in rats from 13 days before mating to the end of the experiment in male rats and 14 days before mating to 7 days of pregnancy in female rats has no effect on the estrus cycle of female rats, the mating rate and conception rate of male and female animals, and the fetus.
Precautions
1. Patients with a history of allergy to this product or any of its components are contraindicated. 2. Patients with a history of aspirin asthma or allergy to other non-steroidal anti-inflammatory drugs are contraindicated. 3. Patients with asthma should use with caution.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.
Drug Interactions
Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Storage
seal.
Packaging Specification
3%
Validity Period
24 months
Manufacturer
Henan Lingrui Biopharmaceutical Co., Ltd.
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Founded in:
2002-06-28 -
Address:
Xinxian Lingrui Industrial Park -
Tax NO.:
914115237425233966 -
Registered Funds:
31.5 million yuan -
Website:
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Email: