Gentamycin Sulfate Chewable Tablets

This product is an aminoglycoside antibiotic. It has good antibacterial effects on various Gram-negative and Gram-positive bacteria, and has good effects on various Enterobacteriaceae such as Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Enterobacter, Serratia and Pseudomonas aeruginosa. Neisseria and Haemophilus influenzae are moderately sensitive to this product. It also has a certain effect on Brucella, Yersinia pestis, Acinetobacter and Campylobacter fetus. It has a good antibacterial effect on about 80% of methicillin-sensitive strains of Staphylococcus (including Staphylococcus aureus and coagulase-negative Staphylococcus), but methicillin-resistant strains are mostly resistant to this product. It has a poor effect on Streptococcus and Streptococcus pneumoniae, and Enterococcus is mostly resistant to this product. When this product is used in combination with beta-lactams, most of them can obtain synergistic antibacterial effects. The mechanism of action of this product is to bind to the 30S subunit of the bacterial ribosome and inhibit the synthesis of bacterial proteins. In recent years, the number of Gram-negative bacteria resistant to gentamicin has increased significantly.

Gentamycin sulfate

This product is white or off-white tablets.

It is used for intestinal infectious diseases such as dysentery and enteritis caused by sensitive bacteria, and can also be used for cleaning the intestinal cavity before surgery.

Chew and take. Adults take 80-160 mg at a time, 3-4 times a day; children take 10-15 mg/kg per day according to body weight, divided into 3-4 times.

1. Rare gastrointestinal symptoms such as nausea, loss of appetite, vomiting, abdominal distension, and skin rash, elevated serum aminotransferase, etc. 2. Occasionally, hearing loss, tinnitus or fullness in the ears (ototoxicity), hematuria, significantly reduced urination frequency or urine volume, loss of appetite, extreme thirst (nephrotoxicity), unsteady gait, dizziness (ototoxicity, vestibular effects), dyspnea, drowsiness, and extreme weakness (neuro-muscle blockade) are seen.

Patients who are allergic to this product or other aminoglycoside antibiotics are contraindicated.

1. When used in combination with other aminoglycosides or used in sequence, it may increase the possibility of ototoxicity, nephrotoxicity and neuromuscular blocking effects. When used in combination with neuromuscular blockers, it may aggravate neuromuscular blocking effects. 2. When used in combination with capreomycin, cisplatin, ethacrynic acid, furosemide or vancomycin or used in sequence, it may increase the possibility of ototoxicity and nephrotoxicity. 3. When used in combination with cephalothin, it may increase nephrotoxicity. 4. When used in combination with polymyxins or used in sequence, it may increase nephrotoxicity and neuromuscular blocking effects. 5. Other nephrotoxic and ototoxic drugs should not be used in combination with this product or used in sequence to avoid aggravating nephrotoxicity or ototoxicity.

Sealed, store in a dry place.

40mg (40,000 units)

Shijiazhuang Dongfang Pharmaceutical Co., Ltd.

• Founded in:

  1993-08-12

• Address:

  No. 528, Cangsheng Road, High-tech Zone, Shijiazhuang, Hebei Province

• Tax NO.:

  91130100601026572T

• Registered Funds:

  80 million yuan

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