Thymopentin for injection
Function and Efficacy
This product is an immune bidirectional regulatory drug. It has the function of inducing and promoting the differentiation, maturation and activation of T lymphocytes and their subsets, regulating the ratio of T lymphocytes to make CD4/CD8 tend to normal; regulating and enhancing the function of human cellular immune function, can promote the maturation of T lymphocytes in peripheral blood after mitogen activation, increase the secretion of various lymphokines (such as: a, gamma interferon, interleukin 2 and interleukin 3) after T cells are activated by various antigens or mitogens, and increase the level of lymphokine receptors on T cells. It also enhances lymphocyte response by activating T helper cells. In addition, this product may affect the chemotaxis of NK precursor cells, which become more cytotoxic after exposure to interferon. Therefore, this product has the function of regulating and enhancing the cellular immune function of the human body.
Ingredients
The main ingredient of this product is thymopentin. The auxiliary materials are mannitol, sodium dihydrogen phosphate, and disodium hydrogen phosphate. Chemical name: N-[N-[N-[Nα-L-arginyl-L-lysyl]-L-α-aspartyl]-L-valyl]-L-tyrosine.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| ThymopentinIngredients |
Immune bidirectional regulatory drug. It has the function of inducing and promoting the differentiation, maturation and activation of T lymphocytes and their subsets, regulating the ratio of T lymphocytes to make CD4/CD8 tend to normal; regulating and enhancing the function of human cellular immune function, can promote the maturation of T lymphocytes in peripheral blood after mitogen activation, increase the secretion of various lymphokines (such as: a, gamma interferon, interleukin 2 and interleukin 3) after T cells are activated by various antigens or mitogens, and increase the level of lymphokine receptors on T cells. It also enhances lymphocyte response by activating T helper cells. In addition, this product may affect the chemotaxis of NK precursor cells, which become more cytotoxic after exposure to interferon. More |
69558-55-0 | 41 |
Appearance
This product is white freeze-dried loose mass or powder.
Indication
This product is suitable for: malignant tumor patients with low immune function caused by radiotherapy and chemotherapy. (1) For patients with chronic hepatitis B over 18 years old. (2) Various primary or secondary T cell deficiency diseases (such as congenital immunodeficiency in children). (3) Certain autoimmune diseases (such as rheumatoid arthritis, systemic lupus erythematosus, etc.). (Lupus erythematosus is an autoimmune disease with a slow onset and insidious occurrence. The clinical manifestations are diverse and varied. It is an autoimmune disease involving many systems and organs. Due to the dysfunction of cellular and humoral immune function, a variety of autoantibodies are produced. It can affect the skin, serous membranes, joints, kidneys and central nervous system, etc., and is characterized by autoimmunity. There are multiple autoantibodies in the patient's body, which not only affect humoral immunity, but also cellular immunity, and the complement system also changes. The pathogenesis is mainly due to the formation of immune complexes. The exact cause is unknown. The condition is a process of repeated attacks and remissions.) (4) Various diseases with low cellular immune function. (5) Adjuvant treatment of tumors.
Usage and Dosage
For intramuscular injection, dissolve in 1 ml of sterile water for injection before use; or dissolve in 250 ml of 0.9% sodium chloride injection and drip intravenously at a slow rate. Take 1 vial at a time, 1 to 2 times a day, 15 to 30 days as a course of treatment, or follow the doctor's advice.
Adverse Reactions
1 Some patients may experience adverse reactions such as nausea, fever, dizziness, chest tightness, and weakness. A few patients may occasionally feel drowsy. 2 Patients with chronic hepatitis B may experience a temporary increase in ALT levels when using this product. If there are no signs of liver failure, this product can still be used.
Precautions
This product is contraindicated for those who are allergic to its ingredients or have undergone organ transplantation.
Special Population Medication
Precautions for children: The safety and effectiveness of this product have not been established for patients under 18 years of age. Precautions for pregnancy and lactation: 1. Animal fertility studies have shown that there is no difference in the abnormal effects on the embryos between the control group and the drug treatment group. It is not yet known whether this drug is harmful to the embryo or affects fertility. Therefore, it can only be used in pregnant women when it is absolutely necessary. Although it has not been confirmed that it is excreted through human milk, it should still be used with caution in lactating women. 2. It is used in combination with many commonly used drugs, including interferon, anti-inflammatory drugs, antibiotics, hormones, analgesics, antihypertensive drugs, diuretics, drugs for the treatment of cardiovascular diseases, central nervous system drugs, and contraceptives, without any interference. 3. When used in combination with interferon, it has a synergistic effect on improving immune function. 4. When used in combination with antibiotics, it can enhance the antibacterial effect. 5. When used in combination with chemotherapy drugs, it can reduce the toxic side effects of chemotherapy. Precautions for the elderly: This product has not been tested and there are no reliable references.
Drug Interactions
1 This product is used in combination with many commonly used drugs, including interferon, anti-inflammatory drugs, antibiotics, hormones, analgesics, antihypertensive drugs, diuretics, drugs for the treatment of cardiovascular diseases, central nervous system drugs, and contraceptives, without any interference. 2 This product is used in combination with interferon, which has a synergistic effect on improving immune function.
Storage
Keep tightly closed in a cool, dark place.
Packaging Specification
1mg
Validity Period
24 months.
Manufacturer
Sinopharm A-Think Pharmaceutical Co., Ltd.
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Founded in:
1997-12-10 -
Address:
No. 111, Yixin Road, Shuangyang Economic Development Zone, Changchun -
Tax NO.:
912201012440638092 -
Registered Funds:
100 million yuan -
Website:
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Email: