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Ibuprofen tablets

Function and Efficacy

This product has analgesic, anti-inflammatory and antipyretic effects. Its mechanism of action is to reduce the synthesis of prostaglandins by inhibiting cyclooxygenase, thereby alleviating tissue congestion and swelling caused by prostaglandins and reducing the sensitivity of peripheral nerve pain. It has an antipyretic effect through the hypothalamic temperature regulation center.

Ingredients

Each tablet of this product contains 0.1g of ibuprofen. The auxiliary materials are: hydroxypropyl cellulose, pregelatinized starch, dextrin, starch, silicon dioxide, magnesium stearate, sodium carboxymethyl starch, sucrose, talc, gelatin, silicone oil, and insect wax.

Name Description Content CAS NO. Manufacturer
IbuprofenIngredients

Analgesic, anti-inflammatory, antipyretic, reduces prostaglandin synthesis by inhibiting cyclooxygenase, reduces tissue congestion and swelling, reduces nerve pain sensitivity, and has an antipyretic effect through the hypothalamic temperature regulation center

More
15687-27-1 54

Indication

It is used to relieve mild to moderate pain such as headache, joint pain, migraine, toothache, muscle pain, neuralgia, and dysmenorrhea. It is also used for fever caused by the common cold or influenza.

Usage and Dosage

Oral administration. Children over 12 years old and adults take 2 tablets at a time. If pain or fever persists, the medication can be repeated once every 4 to 6 hours, and no more than 4 times in 24 hours.

Adverse Reactions

1. Gastrointestinal symptoms include indigestion, stomach burning, stomach pain, nausea, and vomiting, which occur in 16% of long-term users. The above symptoms disappear when the drug is discontinued, and most of the patients who do not stop the drug can tolerate it. A few (1%) develop gastric ulcers and gastrointestinal bleeding, and some suffer from ulcer perforation. 2. Neurological symptoms such as headache, drowsiness, dizziness, and tinnitus are rare, occurring in 1% to 3% of patients. 3. Renal insufficiency is rare, mostly occurring in patients with potential renal disease; but a few users may experience lower limb edema. 4. Other rare symptoms include rash, bronchial asthma attacks, elevated liver enzymes, leukopenia, etc. 5. If gastrointestinal bleeding, liver and kidney damage, visual impairment, abnormal blood counts, and allergic reactions occur during medication, the drug should be discontinued.

Precautions

People who are allergic to aspirin or other non-steroidal anti-inflammatory drugs may have cross-allergic reactions to this product. For asthmatics who are allergic to aspirin, this product may also cause bronchospasm. This product is contraindicated for such patients.

Special Population Medication

Precautions for children: Precautions for pregnancy and lactation: Pregnant women are prohibited. Precautions for the elderly:

Drug Interactions

1. When drinking alcohol or taking it with other non-steroidal anti-inflammatory drugs, it increases gastrointestinal side effects and has the risk of causing ulcers. Long-term use with acetaminophen can increase the toxic side effects on the kidneys. 2. When used with aspirin or other salicylic acid drugs, the efficacy is not enhanced, but the incidence of gastrointestinal adverse reactions and bleeding tendency increases. 3. When used with anticoagulants such as heparin and dicoumarol and platelet aggregation inhibitors, there is an increased risk of bleeding. 4. When used with furosemide, the latter's sodium excretion and antihypertensive effects are weakened. 5. When used with verapamil and nifedipine, the blood concentration of this product increases. 6. This product can increase the blood concentration of digoxin. When used together, pay attention to adjusting the dose of digoxin. 7. This product can enhance the effect of antidiabetic drugs (including oral hypoglycemic drugs). 8. When this product is used with antihypertensive drugs, it can affect the latter's antihypertensive effect. 9. Probenecid can reduce the excretion of this product, increase its blood concentration, and thus increase its toxicity, so it is advisable to reduce the dose of this product when used together. 10. This product can reduce the excretion of methotrexate, increase its blood concentration, and even reach toxic levels, so this product should not be used together with medium or large doses of methotrexate.

Storage

Store in sealed container. Valid for 36 months.

Packaging Specification

0.2 g

Validity Period

36 months

Manufacturer

Huangshan Shengji Pharmaceutical Co., Ltd.

  • Founded in:

    2011-02-18
  • Address:

    No. 1, Huangshan North Gate, Huangshan District, Huangshan City, Anhui Province
  • Tax NO.:

    9134100356898484X4
  • Registered Funds:

    30 million yuan
  • Email:

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