Levofloxacin Hydrochloride Tablets

This product is the levorotatory form of ofloxacin, and its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit the activity of bacterial DNA gyrase (bacterial topoisomerase II) and hinder bacterial replication to achieve antibacterial effect. This product has the characteristics of a broad antibacterial spectrum and strong antibacterial effect. It has strong antibacterial activity against most Enterobacteriaceae, such as Escherichia coli, Klebsiella, Serratia, Proteus, Shigella, Salmonella, Citrobacter, Acinetobacter, as well as Gram-negative bacteria such as Pseudomonas aeruginosa, Haemophilus influenzae, and gonorrhea. It also has good antibacterial effects on some methicillin-sensitive Staphylococci, Streptococcus pneumoniae, Streptococcus pyogenes, hemolytic Streptococci, and Legionella, Mycoplasma, Chlamydia, etc. However, it has poor effects on anaerobic bacteria and enterococci.

The main ingredient of this product: Levofloxacin hydrochloride.

This product is an off-white or light yellow tablet or film-coated tablet, which appears white or light yellow after removing the film coating.

Applicable to infections caused by sensitive bacteria: 1. Urinary and reproductive system infections, including simple and complicated urinary tract infections, bacterial prostatitis, and urethritis caused by Neisseria gonorrhoeae. 2. Respiratory tract infections, including acute bronchial infections and lung infections caused by sensitive Gram-negative bacilli. 3. Gastrointestinal infections, caused by Shigella, Salmonella, enterotoxigenic Escherichia coli, Aeromonas aquaticus, Vibrio parahaemolyticus, etc. 4. Typhoid fever 5. Bone and joint infections 6. Skin and soft tissue infections 7. Systemic infections such as sepsis.

Adults take 200mg-300mg (2-3 tablets) orally per day, divided into 2-3 times. For patients with more serious conditions, the maximum daily dose can be increased to 600mg (6 tablets) orally, divided into 3 times. In addition, the dose can be increased or decreased appropriately according to the type of infection and symptoms.

Adverse reactions may occur during the use of levofloxacin hydrochloride: Digestive system: sometimes nausea, vomiting, abdominal discomfort, diarrhea, loss of appetite, abdominal pain, indigestion, etc.; Allergies: Occasionally edema, urticaria, fever, photosensitivity, and sometimes rash, itching, erythema, etc.; Nervous system: Occasionally tremor, numbness, visual abnormalities, tinnitus, hallucinations, drowsiness, and sometimes insomnia, dizziness, headache, etc.; Kidney: Occasionally increase in blood urea nitrogen; Liver: Transient liver function abnormalities may occur, such as increased serum transaminase and increased serum total bilirubin; Blood: Sometimes anemia, leukopenia, thrombocytopenia, and eosinophilia may occur; The incidence of the above adverse reactions is between 0.1 and 5%, which are generally tolerated and disappear quickly after the end of the course of treatment. If abnormalities are found, they should be observed carefully, and if necessary, the medication can be stopped and appropriate treatment can be carried out.

It is contraindicated for patients who are allergic to quinolones, pregnant and lactating women, and patients under 18 years of age.

Precautions for children: It is forbidden for patients under 18 years old. Precautions for pregnancy and lactation: It is forbidden for pregnant and lactating women. Precautions for the elderly: It should be used with caution in elderly patients. Generally, 0.1g is used once, twice a day, and the interval between medications should be noted.

When this product is used simultaneously with antacids containing magnesium or aluminum, sucralfate, metal cations (such as iron), and zinc-containing multivitamin preparations, it will interfere with the absorption of this product by the gastrointestinal tract, causing the concentration of this drug in various systems to be significantly reduced. Therefore, the time of taking the above-mentioned drugs should be at least 2 hours before or after using this product. Avoid using it simultaneously with theophylline. If it is necessary to use it simultaneously, the blood concentration of theophylline should be monitored and the dosage should be adjusted accordingly. When used simultaneously with warfarin or its derivatives, the prothrombin time or other coagulation tests should be monitored. When used simultaneously with non-steroidal anti-inflammatory drugs, there is a possibility of inducing convulsions. When used simultaneously with oral hypoglycemic drugs, it may cause blood sugar disorders, including hyperglycemia and hypoglycemia. Therefore, blood sugar concentrations should be monitored during medication. Once hypoglycemia occurs, this product should be discontinued immediately and appropriate treatment should be given.

Keep in a light-proof and airtight container.

0.1g (calculated as C18H20FN3O4)

24 months

Huarun Shuanghe Limin Pharmaceutical (Ji'nan) Co., Ltd.

• Founded in:

  2001-06-28

• Address:

  No. 1, Limin Road, Mingshui Street, Zhangqiu District, Jinan City, Shandong Province

• Tax NO.:

  91370181163446867C

• Registered Funds:

  23.85 million yuan

• Email:

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