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Isoproterenol Hydrochloride Injection

Function and Efficacy

Beta receptor agonists have strong stimulatory effects on beta 1 and beta 2 receptors, and have almost no effect on alpha receptors. Main effects: ① Acting on cardiac beta 1 receptors, it increases cardiac contractility, heart rate, conduction, cardiac output and myocardial oxygen consumption. ② Acting on vascular smooth muscle beta 2 receptors, it significantly dilates skeletal muscle blood vessels, kidneys, mesenteric blood vessels and coronary arteries to varying degrees, and reduces total peripheral vascular resistance. Its cardiovascular effects lead to increased systolic blood pressure, decreased diastolic blood pressure, and increased pulse pressure difference. ③ Acting on bronchial smooth muscle beta 2 receptors, it relaxes bronchial smooth muscles. ④ Promotes glycogen and fat decomposition and increases tissue oxygen consumption.

Ingredients

The main ingredient of this product is isoproterenol hydrochloride.

Name Description Content CAS NO. Manufacturer
(-)-ISOPROTERENOL HYDROCHLORIDEIngredients

Beta receptor agonists have strong stimulatory effects on both beta 1 and beta 2 receptors, and have almost no effect on alpha receptors. Main effects: ① Acting on cardiac beta 1 receptors, it increases cardiac contractility, heart rate, conduction, cardiac output and myocardial oxygen consumption. ② Acting on vascular smooth muscle beta 2 receptors, it significantly dilates skeletal muscle blood vessels, kidneys, mesenteric blood vessels and coronary arteries to varying degrees, and reduces total peripheral vascular resistance. Its cardiovascular effects lead to increased systolic blood pressure, decreased diastolic blood pressure, and increased pulse pressure difference. ③ Acting on bronchial smooth muscle beta 2 receptors, it relaxes bronchial smooth muscles. ④ Promotes glycogen and fat decomposition and increases tissue oxygen consumption.

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5984-95-2 11

Appearance

This product is a colorless clear liquid.

Indication

1. Treat cardiogenic or septic shock. 2. Treat complete atrioventricular block and cardiac arrest.

Usage and Dosage

1. For the treatment of cardiac arrest, inject 0.5~1mg into the cardiac cavity. 2. For third degree atrioventricular block, when the heart rate is less than 40 beats per minute, add 0.5~1mg of this product to 200~300ml of 5% glucose injection and drip slowly intravenously.

Adverse Reactions

Common adverse reactions include: dry mouth and throat, palpitations and uneasiness; rare adverse reactions include: dizziness, blurred vision, facial flushing, nausea, increased heart rate, tremor, sweating, fatigue, etc.

Precautions

It is contraindicated in patients with angina pectoris, myocardial infarction, hyperthyroidism and pheochromocytoma.

Drug Interactions

1. When used in combination with other adrenergic drugs, the effect can be enhanced, but the adverse reactions will also increase. 2. When used in combination with propranolol, the effect of this product is antagonized.

Storage

Keep away from light, tightly closed and in a cool place.

Packaging Specification

2ml:1mg

Manufacturer

Southwest Pharmaceutical Co., Ltd.

  • Founded in:

    2015-01-08
  • Address:

    No. 21 Tianxing Bridge, Shapingba District, Chongqing
  • Tax NO.:

    915000003316906249
  • Registered Funds:

    490.146298 million yuan
  • Website:

  • Email:

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