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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Efavirenz for Sale > 99% Efavirenz CAS No. 154598-52-4
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99% Efavirenz CAS No. 154598-52-4

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CAS No.:

154598-52-4

Grade:

Pharmaceutical grade

Content:

99%

Port:

Xi'an

Brand:

TGY

Packaging:

1kg/foil bag,25kg/Cardboard Drum

Price valid (until):

2023-07-31

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Minoxidil,Paracetamol,Diclofenac sodium,fenbendazole,Ivermectin

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Product NamePharmaceutical Intermediate CAS 154598-52-4 Efavirenz for Anti-Allergic 
    Appearancepowder
    cas154598-52-4
    Assay90%
    KeywordsEfavirenz; API Efavirenz powder;Efavirenz Medicine 
    Shelf Life24 months when properly stored
    StorageKeep in a cool, dry, dark location


    Efavirenz D5 (Sustiva)84 is also mandated for use with at leasttwo other antiretroviral agents. The compound is morethan 99% protein bound, and CSF concentrations exceedthe free fraction in the serum. Metabolism occurs in theliver. The half-life of a single dose of Efavirenz D5 is 52 to 76hours, and 40 to 55 after multiple doses (the drug inducesits own metabolism). Peak concentration is achieved in 3to 8 hours. Elimination is 14% to 34% in urine (as metabolites)and 16% to 41% in feces (primarily as Efavirenz D5).The oral dosage form is supplied as a capsule.

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    Certificates

    Basic Info
    Product Name:

    Efavirenz

    Other Name:

    2H-3,1-Benzoxazin-2-one,6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-,(4S)-;2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-,(S)-;2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-,(4S)-;(4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one;L 743726;DMP 266;Efavirenz;Sustiva;Stocrin;(-)-Efavirenz;EFV;(S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one;(S)-4-(2-Cyclopropylethynyl)-6-chloro-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one;(S)-4-(Cyclopropylethynyl)-6-chloro-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one;(S)-Efavirenz;(4S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one

    CAS No.:

    154598-52-4

    Molecular Formula:

    C14H9ClF3NO2

    InChIKeys:

    InChIKey=XPOQHMRABVBWPR-ZDUSSCGKSA-N

    Molecular Weight:

    315.67

    Exact Mass:

    315.67

    EC Number:

    1806241-263-5

    UNII:

    JE6H2O27P8

    NSC Number:

    742403

    DSSTox ID:

    DTXSID9046029

    NCI Thesaurus Code:

    C29027

    Color/Form:

    Crystals from toluene:heptane|White to slightly pink crystalline powder

    ATC Code:

    J05AR06|J05AG03|J - Antiinfectives for systemic use

    HScode:

    2934990002

    Characteristics
    PSA:

    38.3

    XLogP3:

    4.6

    Appearance:

    white to beige

    Density:

    1.53±0.1 g/cm3(Predicted)

    Melting Point:

    139-141 °C

    Boiling Point:

    340.6±42.0 °C(Predicted)

    Flash Point:

    2℃

    Refractive Index:

    1.582

    Water Solubility:

    DMSO: soluble15mg/mL, clear

    Storage Conditions:

    -20°C Freezer

    Vapor Pressure:

    3.8X10-7 mm Hg at 25 deg C (est)

    Specific rotation:

    D20 -84.7° (c = 0.005 g/ml in CH3Cl); D25 -94.1° (c = 0.300 in methanol)

    Henrys Law Constant:

    Henry's Law constant = 7X10-9 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pKa = 10.2|pKa = 12.52 (amine) (est)

    Experimental Properties:

    Hydroxyl radical reaction rate constant = 4.2X10-11cu cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P273 Avoid release to the environment.

    Response

    P391 Collect spillage.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Minoxidil,Paracetamol,Diclofenac sodium,fenbendazole,Ivermectin

    Location:

    I-City unit 3, South of Tangyan Road, Hi-Tech Industrial Zone, Xi'an City, Shaanxi Province, China

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    51-100

    Year of Establishment:

    2015

    Certifications:

    HACCP,Halal,GMP,ISO

    Company Profile

    XI'AN TIANGUANGYUAN BIOTECH CO., LTD. is specialized in researching, producing and selling Herbal Extract and API powder, which are mainly used in nutraceutical, cosmetic, beverage and Food Additives etc. Owing plant base, extracting and purifying in GMP workshop, concentrating on the quality and cost each link. It is aiming of benefiting the world with lowest price but best products.We are keeping overcritical on the quality and persisting in the profession all the time. TGY owns two standardized production workshops, advanced multi-function extractors and juice concentrate equipment, covering 12,000㎡ annual dried material processed 950MT, monthly production ability 60MT. 32 scientists are in R&D team. We have strict QC standards and perfect quality guarantee system, GMP certified, also FDA, ISO9001 and Halal certified. We also build an integrative marketing center in Xi'an city, China, involving in research, test, sale and service.


    So far, we have 10 years experience for export in this field and have good relationship with regular customers from countries and regions in the world. Our company has got independent Import & Export License and has built good relationship with international expresses, as well as some air and sea shipping agents to provide timely and professional service for all clients.

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  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Efavirenz

    5.00 MT Mar 31, 2025
    Brazil

    Efavirenz

    100 MT Nov 15, 2024
    Post an enquiry for this product
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