Candesartan
1 Inquiries
139481-59-7
99%
2026-08-07
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Candesartan Cat No CEI-0346 Description Candesartan Alias Atacand, Blopress, Amias, Ratacand CAS No 139481-59-7 Molecular Weight 440.45 Purity >99% Storage 2 years at -20centigrade Powder Synonyms Atacand, Blopress, Amias, Ratacand Targets angiotensin II receptor Molecular Formula C24H20N6O3 Solubility DMSO 88 mg/mL, Water In vitro Candesartan binds with high specificity to the angiotensin II AT1 receptors in CHO-AT1 cells. Candesartan does not affect cell viability or proliferation but increases the expression of VEGF and interleukin-8 in the cultured medium of KU-19-19 cells. Candesartan (0.1 nM) could reduce the maximal contractile response to angiostensin II by approximately 50%. category Cardiovascular Agents(c1135) cas_num 139481-59-7 Basic Info-
Product Name:
Candesartan
Other Name:1H-Benzimidazole-7-carboxylic acid,2-ethoxy-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-;1H-Benzimidazole-7-carboxylic acid,2-ethoxy-1-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-;2-Ethoxy-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid;CV 11974;Candesartan;Candesartan M1;2-Ethoxy-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid;2-Ethoxy-1-[[2′-(1H-tetrazol-5-yl)-1,1′-biphenyl-4-yl]methyl]-7-benzimidazolecarboxylic acid;2-Ethoxy-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid;3-[[2′-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-ethoxy-3H-benzimidazole-4-carboxylic acid;1-((2′-(1H-Tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid;2-Ethoxy-1-([4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl)-1H-1,3-benzodiazole-7-carboxylic acid;875515-04-1
CAS No.:139481-59-7
Molecular Formula:C24H20N6O3
InChIKeys:InChIKey=HTQMVQVXFRQIKW-UHFFFAOYSA-N
Molecular Weight:440.45
Exact Mass:440.45
EC Number:1806241-263-5
UNII:S8Q36MD2XX
NSC Number:759858
DSSTox ID:DTXSID0022725
NCI Thesaurus Code:C65284
Color/Form:Colorless crystals from ethyl acetate + methanol
ATC Code:C - Cardiovascular system
HScode:29419000
Categories:
Characteristics-
PSA:
119
XLogP3:4.1
Appearance:Solid
Density:1.41±0.1 g/cm3(Predicted)
Melting Point:183-185 °C
Boiling Point:754.8±70.0 °C(Predicted)
Flash Point:410.3±35.7 °C
Refractive Index:1.719
Water Solubility:soluble in ethyl acetate, methanol, water (<1 mg/ml at 25°C), DMSO (88 mg/ml at 25°C), and ethanol (1 mg/ml at 25°C).
Storage Conditions:-20°C Freezer
Vapor Pressure:1.8X10-18 mm Hg at 25 deg C (est)
Henrys Law Constant:Henry's Law constant = 8.7X10-19 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa1 = 2.45 (carboxylic acid); pKa2 = 6.70 (N-heterocyclic) (est)
Experimental Properties:Colorless crystals from ethanol + water, mp 163 °C (decomposes). Also reported as white to off-white powder, sparingly soluble in methanol. Practically insoluble in water. /Candesartan 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl ester/|White to off-white powder, mw - 610.67. Practically insoluble in water and sparingly soluble in methanol. ... a racemic mixture containing one chiral center at the cyclohexyloxycarbonyloxy ethyl ester group. Following oral administration ... undergoes hydrolysis at the ester link to form the active drug, candesartan, which is achiral. /Cilexetil/|White, or practically white, crystalline powder, mw - 297.72 .. Slightly soluble in water, but freely soluble in hydroxide solution /Cilexetil hydrochlorothiazide/|Hydroxyl radical reaction rate constant = 4.96X10-11 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
India
Candesartan
2000 KG May 26, 2025 Post an enquiry for this product
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