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99% 2-Chloro-5-nitropyridine CAS 4548-45-2

Name: 99% 2-Chloro-5-nitropyridine CAS 4548-45-2
Brand: Entrepreneur
SKU: pr2309281225
Price: 1 USD
Availability: InStock

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CAS No.:

4548-45-2

Grade:

Chemical Grade

Content:

99%

Port:

Shanghai

Brand:

Entrepreneur

Packaging:

50kg/bag or as per your particular request.

Price valid (until):

2023-12-31

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Beijing Entrepreneur Science & Trading Co., Ltd.

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Flavor & Fragrance Ingredients,Plasticizer,API,Pharmaceutical Intermediates,Thermal Powder,Plant Extract

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Product Description
Seller Information

Description

2-Chloro-5-nitropyridine, also known as 6-Chloro-3-nitropyridine, 5-Nitro-2-chloropyridine or NSC 4468, is widely used as an intermediate in the synthesis of various pharmaceuticals (like Sonidegib), agrochemicals, and other organic compounds. Its functional groups make it a versatile building block for the introduction of specific chemical moieties during synthesis. The presence of the chloro and nitro groups allows for further chemical modifications and reactions, leading to the creation of more complex molecules.

Due to its reactivity and versatility, 2-Chloro-5-nitropyridine finds applications in the pharmaceutical industry for the synthesis of drugs and active pharmaceutical ingredients (APIs). It is also utilized in the production of agrochemicals, dyes, pigments, and other fine chemicals.

It is important to handle 2-Chloro-5-nitropyridine with care, following proper safety protocols and guidelines, as it can be harmful if ingested, inhaled, or in contact with the skin.

Features

❶ Chemical properties: 2-Chloro-5-nitropyridine is a white crystalline solid with a distinctive odor. It has a molecular formula of C5H3ClN2O2 and a molecular weight of 158.54 g/mol. It is sparingly soluble in water but soluble in organic solvents such as ethanol, methanol, and acetone.

❷ Functional groups: The compound contains both a chlorine atom (Cl) and a nitro group (NO2) attached to the pyridine ring. These functional groups provide reactivity and enable the compound to participate in various chemical reactions.

❸ Reactivity: 2-Chloro-5-nitropyridine is reactive and can undergo substitution, reduction, and other chemical transformations. The presence of the chlorine and nitro groups allows for further derivatization and modification to create new compounds with desired properties.

❹ Versatility: Due to its reactivity and functional groups, 2-Chloro-5-nitropyridine serves as a versatile building block in organic synthesis. It can be used as an intermediate to synthesize a wide range of pharmaceuticals, agrochemicals, dyes, and other fine chemicals.

Applications

1. Pharmaceutical synthesis

2-Chloro-5-nitropyridine serves as a valuable intermediate in the synthesis of various pharmaceutical compounds (like Sonidegib). It can be used in the production of antihypertensive drugs, antimicrobial agents, anti-inflammatory drugs, and other therapeutically active substances.

2. Agrochemicals

The compound finds use in the synthesis of agrochemicals such as herbicides, insecticides, and fungicides. These agricultural chemicals play a crucial role in crop protection and pest control, contributing to improved agricultural yields and quality.

3. Dye synthesis

2-Chloro-5-nitropyridine is utilized in the production of dyes and pigments. It can be incorporated into dye molecules to impart specific colors and properties, making it valuable in the textile, printing, and dyeing industries.

4. Chemical research

The compound is utilized in chemical research as a versatile building block and reagent. Its reactivity and functional groups allow chemists to create and modify molecules for various research purposes, including the development of new materials, catalysts, and chemical processes.

5. Other applications

2-Chloro-5-nitropyridine may have applications in other areas such as electrochemistry, polymer synthesis, and organic electronics. Its unique chemical properties make it useful in diverse scientific and industrial fields.

Specifications

Product Name	2-Chloro-5-nitropyridine
Cas No.	4548-45-2
Molecular Formula	C5H3ClN2O2
Molecular Weight	158.54
Appearance	White powder
Density	1.489
Purity	99% Min
Solubility	Soluble in hot methanol. sparingly soluble in water.
Boiling point	256.6 °C at 760 mmHg
Melting point	106-110℃
Flash point	109 °C
Vapour	0.02mmHg at 25°C
Refractive index	1.587
SMILES	N(=O)(=O)C=1C=CC(Cl)=NC1
InChI Key	InChIKey=BAZVFQBTJPBRTJ-UHFFFAOYSA-N

About Packaging

Storage

→

Keep in dark place, sealed in dry, room temperature.

Package

→

50kg/bag or as per your particular request.

Certificates

Basic Info

Product Name:

2-Chloro-5-nitropyridine

Other Name:

Pyridine,2-chloro-5-nitro-;2-Chloro-5-nitropyridine;6-Chloro-3-nitropyridine;5-Nitro-2-chloropyridine;3-Nitro-6-chloropyridine;NSC 4468

CAS No.:

4548-45-2

Molecular Formula:

C5H3ClN2O2

InChIKeys:

InChIKey=BAZVFQBTJPBRTJ-UHFFFAOYSA-N

Molecular Weight:

158.54252

Exact Mass:

158.54

EC Number:

224-908-3

NSC Number:

4468

DSSTox ID:

DTXSID70196525

HScode:

2933399090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

58.7

XLogP3:

2.2

Appearance:

Light yellow to beige Powder

Density:

1.5±0.1 g/cm3

Melting Point:

81-82 °C

Boiling Point:

256.6°C at 760 mmHg

Flash Point:

109.0±21.8 °C

Refractive Index:

1.587

Water Solubility:

Solubility in hot methanol. Insoluble in water.

Storage Conditions:

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

See More 2-Chloro-5-nitropyridine Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 2-Chloro-5-nitropyridine Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Flavor & Fragrance Ingredients,Plasticizer,API,Pharmaceutical Intermediates,Thermal Powder,Plant Extract

Location:
Room 902, 917, Hua Teng Bei Tang Business Plaza, No.37 Nan Mo Fang Road, Chao Yang District, Bei Jing, China

Payment Terms:
L/C,100% TT in advance

Average lead Time:
5

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2001

Beijing Entrepreneur Science & Trading Co., Ltd. was established in the year 2001. We are focused on import and export business of high quality specialty chemicals. Since its establishment, relying on diligent efforts, spirit of enterprising and professional services, the company has established extensive cooperation with world-famous chemical manufacturers and gained a good reputation in China chemical industry.
We have stable distribution cooperation with world leading suppliers from America, Europe, Japan and Taiwan. We are distributors of Ames Advantage Material, Novamet, Lanxess, Momentive, Potters, Rhodia, Roquette, Oerlikon Metco, Inovyn, KJ Chemical, Tokuyama, Mitsubishi Chemical, Chang Chun Group, etc.
Our products selling in China include Conductive Powder, Thermal Conductive Powder, Microwave Absorbing Powder, Acrylamide Functional Monomer and Special UV Monomer, Special Epoxy Resin, Mercaptan Curing Agent, Silane, Fumed Silica and Precipitated Silica, PVC Paste Resin, PVA, Carbon Black, Modified Starch, Photocatalyst, Formaldehyde Capture agent, Root Blocking Agent, Platinum Catalyst, Vinyl Silicone Oil, Surfactant, etc
In 2014, the company entered the chemical export business. Based on our understanding of China chemical market, we select most qualified suppliers. We are able to source raw materials directly from factories. Most of our partners are the largest factory in China with over 20 years history. They have huge annual outputs, and hold ISO9001, ISO14001, GMP, KOSHER, HALAL, FDA, GSP, etc. certificates.
Our export products include Conductive Powder, Thermal Conductive Powder, Plant Extract, Inorganic Powder, Plasticizer, PVC Paste Resin, Silane, Flavors and Fragrances, Salen Catalysts and Ligands, Organic Intermediates, Pharmaceutical Intermediates.
We continue to add new product lines and chemical distribution centers to service a wider range of industries.
We hope to become a bridge between China chemical manufacturers and world-wide customers, continue to provide professional products and solutions for customers overseas. We look forward to considerable development in export business of specialty chemicals.
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