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Home > Biochemical Engineering > Biosynthetic Natural Products > Shikimic acid for Sale > Most Professional Factory Supply High Qulity Shikimic Acid CAS 138-59-0
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Most Professional Factory Supply High Qulity Shikimic Acid CAS 138-59-0

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Unit Price: Get Latest Price
CAS No.:

138-59-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Durban

Brand:

Custom

Packaging:

As per customer requirement

Price valid (until):

2024-05-21

Company Type:
Distributor
Location:
South Africa
Qualification:
Main Products:

Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


                                                  1. Introduction to Shikimic Acid (138-59-0): Shikimic acid (138-59-0) is a naturally occurring compound found in various plants, particularly in the seeds of the Chinese star anise (Illicium verum). It plays a crucial role in the biosynthesis of aromatic amino acids and serves as a precursor for the production of pharmaceuticals and flavors.

                                                  2. Chemical Structure of Shikimic Acid (138-59-0): Shikimic acid (138-59-0) is a cyclohexene derivative with a carboxylic acid functional group. Its chemical structure consists of a cyclohexane ring fused to a cyclohexene ring, with a carboxyl group attached at the C-3 position.

                                                  3. Natural Sources of Shikimic Acid (138-59-0): Shikimic acid (138-59-0) is primarily obtained from natural sources such as the Chinese star anise and certain species of pine trees. It is extracted from the seeds of these plants and subsequently purified for various industrial applications.

                                                  4. Biosynthesis Pathway of Shikimic Acid (138-59-0): Shikimic acid (138-59-0) is synthesized in plants via the shikimate pathway, a metabolic route that converts simple carbon sources into aromatic compounds. This pathway plays a vital role in the production of essential aromatic amino acids and secondary metabolites.

                                                  5. Industrial Uses of Shikimic Acid (138-59-0): Shikimic acid (138-59-0) serves as a key starting material for the semi-synthetic production of oseltamivir (Tamiflu), a widely used antiviral medication for the treatment of influenza. Its role in pharmaceutical synthesis underscores its significance in the pharmaceutical industry.

                                                  6. Antiviral Properties of Shikimic Acid (138-59-0): Research suggests that shikimic acid (138-59-0) may possess inherent antiviral properties, which could contribute to its efficacy in the treatment of influenza and other viral infections. Further studies are ongoing to explore its potential therapeutic applications.

                                                  7. Flavoring Agent in the Food Industry: Shikimic acid (138-59-0) is utilized as a flavoring agent in the food industry, imparting a characteristic taste profile to various food and beverage products. Its natural origin and aromatic properties make it a desirable ingredient in culinary applications.

                                                  8. Potential Health Benefits of Shikimic Acid (138-59-0): Beyond its role in antiviral therapy, shikimic acid (138-59-0) has been investigated for its potential health-promoting effects, including antioxidant and anti-inflammatory properties. These properties may contribute to its therapeutic potential in various health conditions.

                                                  9. Safety Considerations and Regulations: Shikimic acid (138-59-0) is generally regarded as safe for consumption when used in accordance with established guidelines. Regulatory agencies worldwide oversee its safety and permissible levels in food and pharmaceutical products to ensure consumer protection.

                                                  10. Extraction and Purification Processes: The extraction of shikimic acid (138-59-0) from plant sources involves solvent-based methods followed by purification steps to isolate the compound in its pure form. These processes require careful optimization to achieve high yields and purity levels.

                                                  11. Synthetic Approaches to Shikimic Acid (138-59-0): In addition to extraction from natural sources, shikimic acid (138-59-0) can be synthesized through chemical routes starting from simple precursor molecules. Synthetic methodologies enable the production of shikimic acid on a larger scale for commercial applications.

                                                  12. Biotechnological Production Methods: Biotechnological approaches, including microbial fermentation and metabolic engineering, offer alternative strategies for the sustainable production of shikimic acid (138-59-0). These methods leverage microbial cell factories to biosynthesize shikimic acid from renewable feedstocks.

                                                  13. Environmental Impact and Sustainability: Sustainable sourcing and production practices are crucial to minimize the environmental impact associated with shikimic acid (138-59-0) production. Efforts to promote eco-friendly extraction methods and reduce waste generation contribute to its sustainable utilization.

                                                  14. Research Trends and Future Directions: Ongoing research endeavors focus on exploring novel applications of shikimic acid (138-59-0) in drug discovery, nutraceuticals, and functional foods. Advancements in synthetic biology and bioprocess engineering hold promise for expanding its industrial relevance.

                                                  15. Collaborative Efforts and Industry Partnerships: Collaboration between academia, industry, and government agencies plays a vital role in advancing the science and technology related to shikimic acid (138-59-0). Collaborative research initiatives foster innovation and drive the development of new products and processes.

    Items Specifications
    Chemical Structure Shikimic acid is a cyclohexene derivative and a white crystalline compound.
    Molecular Formula C₇H₁₀O₅
    IUPAC Name (3R,4S,5R)-3,4,5-Trihydroxycyclohex-1-ene-1-carboxylic acid
    Synonyms 3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid; (+)-Shikimic acid; 3,4,5-Trihydroxybenzoic acid
    Chemical Class Cyclohexene carboxylic acid
    Solubility Soluble in water and ethanol.
    Source Originally extracted from the seed pods of the Chinese star anise (Illicium verum) and certain other plants.
    Biological Role A key intermediate in the biosynthesis of aromatic amino acids, such as phenylalanine and tyrosine.
    Health Benefits Used in the synthesis of the antiviral drug oseltamivir (Tamiflu), which is effective against influenza.
    Metabolism Metabolized in plants through the shikimate pathway, a central metabolic route for aromatic compound synthesis.
    Dietary Sources Present in trace amounts in various plants, particularly those involved in the shikimate pathway.
    Pharmacological Use Used in pharmaceuticals for the synthesis of various compounds, including antiviral and antimicrobial agents.
    Bioavailability Absorption and metabolism can vary depending on the route of administration and specific formulation.
    Structural Isomers Exists as a single compound without structural isomers.
    Research Areas Investigated for its potential applications in drug synthesis, particularly in the development of antiviral drugs.
    Industrial Uses Widely used as a starting material in the industrial production of oseltamivir phosphate and other chemicals.


      Product Detail  


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    Basic Info
    Product Name:

    Shikimic acid

    Other Name:

    1-Cyclohexene-1-carboxylic acid,3,4,5-trihydroxy-,(3R,4S,5R)-;1-Cyclohexene-1-carboxylic acid,3,4,5-trihydroxy-,[3R-(3α,4α,5β)]-;(3R,4S,5R)-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid;Shikimic acid;[3R-(3α,4α,5β)]-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid;(-)-Shikimic acid;L-Shikimic acid;NSC 59257;(-)-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid;22574-35-2

    CAS No.:

    138-59-0

    Molecular Formula:

    C7H10O5

    InChIKeys:

    InChIKey=JXOHGGNKMLTUBP-HSUXUTPPSA-N

    Molecular Weight:

    174.15

    Exact Mass:

    174.15

    BRN:

    4782717

    EC Number:

    205-334-2

    UNII:

    29MS2WI2NU

    DSSTox ID:

    DTXSID4032039

    Color/Form:

    Needles from methanol/ethyl acetate

    HScode:

    29181980

    Characteristics
    PSA:

    98

    XLogP3:

    -1.51620

    Appearance:

    White to light beige or light gray Powder

    Density:

    1.52 g/cm3 (27.2℃)

    Melting Point:

    183-184.5 °C

    Boiling Point:

    185-187 °C

    Flash Point:

    210.1ºC

    Refractive Index:

    -180 ° (C=1, H2O)

    Water Solubility:

    H2O: 18 g/100 mL (20 ºC)

    Storage Conditions:

    -20°C Freezer

    Vapor Pressure:

    4.45E-08mmHg at 25°C

    Toxicity:

    Peritoneal-mouse LD50: 600 mg/kg

    Flammability characteristics:

    Flammable, spicy and irritating smoke emitted from the fire

    Specific rotation:

    -180 º (c=4, H2O 25 ºC)

    Dissociation Constants:

    K = 7.1X10-5 at 14.1 °C

    Collision Cross Section:

    149.5 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|140.55 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|136.3 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|137.7 Ų [M-H]-

    Experimental Properties:

    SUBLIMES; SPECIFIC OPTICAL ROTATION: -161 °C/D (C= 0.57 IN METHANOL), -183.8 DEG @ 18 °C/D (C= 4.03 IN WATER)|NEEDLES FROM METHANOL/ETHYL ACETATE; MP: 191-192 °C; MAX ABSORPTION (ETHANOL): 212 NM (E= 8200) /(+ OR -)-FORM/

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

    Location:

    13 PROTEA PARK MILKWOOD STREET RANGEVIEW GAUTENG 1739

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment

    Average lead Time:

    60

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2012

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    New Zealand

    98% Shikimic Acid (HPLC)

    25 KG Apr 10, 2024
    India

    SHIKIMIC ACID

    25 MT May 11, 2024
    Post an enquiry for this product
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