Best Quality USP Standard Finasteride CAS 98319-26-7 for Anti-hair loss with GMP/CEP/DMF

Finasteride More Info

Finasteride is a synthetic medication primarily used for treating benign prostatic hyperplasia (BPH) and male pattern hair loss (androgenetic alopecia). It functions as a selective inhibitor of the enzyme 5-alpha-reductase, which converts testosterone into dihydrotestosterone (DHT), a hormone implicated in both conditions.

Mechanism of Action

Finasteride specifically inhibits the Type II isoenzyme of 5-alpha-reductase, which is predominantly found in the prostate, seminal vesicles, and hair follicles. By blocking this enzyme, finasteride reduces DHT levels significantly—up to 91% in prostate tissue and about 70% in serum concentrations. This reduction leads to decreased stimulation of androgen receptors in the prostate, resulting in reduced prostate size and alleviation of urinary symptoms associated with BPH. The inhibition also helps prevent hair loss by reducing the effects of DHT on hair follicles

Uses

1. Benign Prostatic Hyperplasia (BPH):
Finasteride is prescribed at a dosage of 5 mg once daily to help reduce prostate size, alleviate urinary symptoms, and potentially delay the need for surgery.
2. Male Pattern Hair Loss:
For treating hair loss, the typical dosage is 1 mg once daily. It may take several months (usually 3 months or more) to notice improvements in hair growth and density.

Routes of Administration

Finasteride is administered orally in tablet form. It can be taken with or without food, and its absorption is not significantly affected by dietary intake. The bioavailability of finasteride is approximately 65%, with peak plasma concentrations occurring within 1-2 hours post-administration

Safety and Side Effects

While finasteride is generally well-tolerated, it can cause side effects, including:
Sexual dysfunction (decreased libido, erectile dysfunction)
Ejaculation disorders
Breast tenderness or enlargement
Potentially increased risk of high-grade prostate cancer with long-term use
These side effects may persist even after discontinuation of the medication. Regular monitoring by healthcare providers is recommended to manage any adverse effects effectively.

Pharmacokinetics

Absorption: The drug is well absorbed after oral administration, with a bioavailability of about 65%.
Distribution: Finasteride has a volume of distribution of approximately 76 L and is about 90% protein-bound in plasma.
Metabolism: It undergoes extensive hepatic metabolism primarily via the cytochrome P450 3A4 enzyme, producing metabolites that retain less than 20% of the pharmacological activity of finasteride.
Elimination: The elimination half-life ranges from 4.7 to 7.1 hours, with longer half-lives observed in older adults. Approximately 57% of the drug is excreted via feces and 39% through urine.

Precautions

Not for Women: Finasteride is not approved for use in women, particularly those who are pregnant or breastfeeding, due to potential risks to fetal development.
Monitoring: Regular monitoring of prostate-specific antigen (PSA) levels is recommended for men taking finasteride for BPH, as the drug can lower PSA levels and potentially mask prostate cancer.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

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Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.