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High Quality 99% Eprosartan Mesylate CAS 144143-96-4 Powder Fast Shipment Good Price buy - large image1
High Quality 99% Eprosartan Mesylate CAS 144143-96-4 Powder Fast Shipment Good Price buy - image1
High Quality 99% Eprosartan Mesylate CAS 144143-96-4 Powder Fast Shipment Good Price buy - image2
High Quality 99% Eprosartan Mesylate CAS 144143-96-4 Powder Fast Shipment Good Price buy - image3
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High Quality 99% Eprosartan Mesylate CAS 144143-96-4 Powder Fast Shipment Good Price

Unit Price: Get Latest Price
CAS No.:

144143-96-4

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

Hangzhou

Brand:

HyperChem

Packaging:

1kg/Bag

Price valid (until):

2025-01-11

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Description

    Name

    Eprosartan Mesylate

    CAS number

    144143-96-4

    Synonym

    Eprosartan Mesylate; Teveten; Futuran; Navixen; Regulaten; SK and F 108566;

    Description

    Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. It is marketed in the United States as Teveten by Abbvier. Eprosartan is sometimes paired with hydrochlorothiazide, whereupon it is marketed in the US as Teveten HCT and elsewhere as Teveten Plus.The drug acts on the renin-angiotensin system to decrease total peripheral resistance in two ways. First, it blocks the binding of angiotensin II to AT1 receptors in vascular smooth muscle, causing vascular dilatation. Second, it inhibits sympathetic norepinephrine production, further reducing blood pressure. As with other angiotensin II receptor antagonists, eprosartan is generally better tolerated than enalapril (an ACE inhibitor), especially among the elderly.

    Structure

    Shop High Quality 99% Eprosartan Mesylate CAS 144143-96-4 Powder Fast Shipment Good Price-Detailed Image 1

    Molecular Formula

    C24H28N2O7S2

    Molecular Weight

    520.62 g/mol

    Appearance

    White Powder

    Quality Standard

    99%

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Dry, dark and at 2~8 for short term (days to weeks) or -20 for long term (months to years).

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag, Bottle

    Commercial package

    Aluminium Tin

    Origin

    China

    Eprosartan Mesylate More Info


    Eprosartan mesylate is an antihypertensive medication belonging to the class of drugs known as angiotensin II receptor blockers (ARBs). It is used primarily for the management of high blood pressure (hypertension). Below is a detailed overview of this product:

    Mechanism of Action

    Eprosartan works by selectively blocking the action of angiotensin II, a potent vasoconstrictor that contributes to increased blood pressure. By inhibiting angiotensin II from binding to its receptors, Eprosartan causes vasodilation (widening of blood vessels), which results in a decrease in blood pressure. This medication also decreases the secretion of aldosterone, leading to increased excretion of sodium and water, further helping to lower blood pressure.

    Indications

    Eprosartan is indicated for:

    Hypertension:  It is primarily used for the treatment of essential hypertension in adults.

    Dosing and Administration

    Eprosartan is administered orally, typically in tablet form. The common dosing regimen includes:

    Initial Dose:  The usual starting dose is 400 mg once daily.

    Maintenance Dose:  Based on the patient's response and tolerance, the dose may be adjusted, with a typical maintenance dosage ranging from 400 mg to 800 mg per day, taken in one or two divided doses.

    Side Effects

    Common side effects associated with Eprosartan include:

    Dizziness or Lightheadedness:  These symptoms may occur, particularly after the initial dose or when the dosage is increased.

    Fatigue:  Some patients may experience tiredness.

    Gastrointestinal Symptoms:  Dyspepsia (indigestion) and diarrhea can occur.

    Hyperkalemia:  Elevated potassium levels in the blood may result, necessitating monitoring of serum potassium levels.

    Angioedema:  Although rare, there is a risk of angioedema, which involves swelling of the face, lips, or throat and requires immediate medical attention.

    Contraindications and Precautions

    Contraindications:  Eprosartan should not be used in individuals with a known hypersensitivity to the drug or in patients who are pregnant. It is also contraindicated in patients with severe renal impairment.

    Precautions:  Caution is advised in patients with renal artery stenosis, history of angioedema, or those with pre-existing electrolyte imbalances. Regular monitoring of blood pressure and renal function is recommended during treatment, particularly after dose adjustments.

    Conclusion

    Eprosartan mesylate is an effective option for the treatment of hypertension, providing a mechanism that facilitates vasodilation and promotes better blood pressure control. Like other ARBs, it is generally well-tolerated, but careful monitoring for potential side effects, contraindications, and interactions with other medications is essential for ensuring safe and effective use. Patients are encouraged to work closely with healthcare providers for optimal management of their condition and to address any concerns regarding their treatment.

    Eprosartan mesylate is an antihypertensive medication belonging to the class of drugs known as angiotensin II receptor blockers (ARBs). It is used primarily for the management of high blood pressure (hypertension). Below is a detailed overview of this product:
    Mechanism of Action
    Eprosartan works by selectively blocking the action of angiotensin II, a potent vasoconstrictor that contributes to increased blood pressure. By inhibiting angiotensin II from binding to its receptors, Eprosartan causes vasodilation (widening of blood vessels), which results in a decrease in blood pressure. This medication also decreases the secretion of aldosterone, leading to increased excretion of sodium and water, further helping to lower blood pressure.
    Indications
    Eprosartan is indicated for:
    Hypertension: It is primarily used for the treatment of essential hypertension in adults.
    Dosing and Administration
    Eprosartan is administered orally, typically in tablet form. The common dosing regimen includes:
    Initial Dose: The usual starting dose is 400 mg once daily.
    Maintenance Dose: Based on the patient's response and tolerance, the dose may be adjusted, with a typical maintenance dosage ranging from 400 mg to 800 mg per day, taken in one or two divided doses.
    Side Effects
    Common side effects associated with Eprosartan include:
    Dizziness or Lightheadedness: These symptoms may occur, particularly after the initial dose or when the dosage is increased.
    Fatigue: Some patients may experience tiredness.
    Gastrointestinal Symptoms: Dyspepsia (indigestion) and diarrhea can occur.
    Hyperkalemia: Elevated potassium levels in the blood may result, necessitating monitoring of serum potassium levels.
    Angioedema: Although rare, there is a risk of angioedema, which involves swelling of the face, lips, or throat and requires immediate medical attention.
    Contraindications and Precautions
    Contraindications: Eprosartan should not be used in individuals with a known hypersensitivity to the drug or in patients who are pregnant. It is also contraindicated in patients with severe renal impairment.
    Precautions: Caution is advised in patients with renal artery stenosis, history of angioedema, or those with pre-existing electrolyte imbalances. Regular monitoring of blood pressure and renal function is recommended during treatment, particularly after dose adjustments.
    Conclusion
    Eprosartan mesylate is an effective option for the treatment of hypertension, providing a mechanism that facilitates vasodilation and promotes better blood pressure control. Like other ARBs, it is generally well-tolerated, but careful monitoring for potential side effects, contraindications, and interactions with other medications is essential for ensuring safe and effective use. Patients are encouraged to work closely with healthcare providers for optimal management of their condition and to address any concerns regarding their treatment.



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    FAQ


    Q1. Can I get a free sample?

    We can send you a samll free sample, and you only need to pay for the shipping cost.

     

    Q2. What is the HyperChem payment term?

    T/T in advance
    LC at sight
    DP at sight

    Bank transfer

    PayPal

    Bitcoin...

     

    Q3. What is HyperChem shipment policy?

    Our policy is to strive for the quickest shipment time possible.

    For ready stock samples, they are usually shipped within 3 working days after payment received.
    For non-ready stock, please contact HyperChem sales team to negotiate.

     

    Q4. What is HyperChem shipment term?

    By Express  
    FedEx  UPS  DHL  EMS                               
    Fast: 3-7 days around, high cost, door to door service

    By Air                                        
    Suitable for more than 50kg 
    Fast: 3-7 days, hight cost, port to port, professional broker needed 

    By Sea
    Suitable for more than 500kg      
    Fast: 7-45 days, low cost, port to port, professional broker needed 

     

    We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

     

    Q5. What HyperChem will provide after shipment?

    For sample orders: 
    After shipment is done, an timely email including:

    1. Track details (Fedex /TNT/DHL/EMS Track number)
    2. Packaging photo
    3. COA, MSDS, etc
    4. Dispatch date & Estimated arriving time
    5. Shipping invoice

    For commercial orders:
    A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

    Basic Info
    Product Name:

    2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)-, methanesulfonate (1:1)

    Other Name:

    2-Thiophenepropanoic acid,α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-,(αE)-,methanesulfonate (1:1);2-Thiophenepropanoic acid,α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-,(E)-,monomethanesulfonate;2-Thiophenepropanoic acid,α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-,(αE)-,monomethanesulfonate;SKF 108566J;Eprosartan mesylate;Eprosartan methanesulfonate

    CAS No.:

    144143-96-4

    Molecular Formula:

    C23H24N2O4S.CH4O3S

    InChIKeys:

    InChIKey=DJSLTDBPKHORNY-XMMWENQYSA-N

    Molecular Weight:

    520.61832

    Exact Mass:

    520.133789

    EC Number:

    1806241-263-5

    HScode:

    29349990

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    183

    XLogP3:

    5.32920

    Appearance:

    white to off-white

    Density:

    1.26 g/cm3

    Melting Point:

    248-250°

    Boiling Point:

    660.6°C at 760 mmHg

    Flash Point:

    353.3ºC

    Water Solubility:

    DMSO: >10mg/mL

    Storage Conditions:

    room temp

    Vapor Pressure:

    2.37E-18mmHg at 25°C

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Eye irritation, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

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