Glycine phosphate

Glycine Phosphate: Introduction and Key Properties

Chemical Identity

Glycine phosphate, also known as 2-aminoacetic acid phosphate, is an organophosphorus compound combining glycine (the simplest amino acid) with a phosphate group. Its molecular formula is C₂H₈NO₆P (or C₂H₅NO₆P⁻³ in ionic form), with a molecular weight of 173.06 g/mol24. Two CAS numbers are associated with this compound: 71295-98-2 (commonly referenced) and 75194-99-9 (less frequently cited, possibly a variant)23.

Physical and Chemical Properties

• Appearance: Typically supplied as a white crystalline powder24.

• Solubility: Moderately soluble in water, with solubility enhanced by heating. Also dissolves in polar solvents like ethanol4.

• Stability: Hygroscopic (absorbs moisture) and decomposes at high temperatures4.

Synthesis and Production

Glycine phosphate is synthesized through reactions involving glycine and phosphoric acid derivatives. While detailed synthesis routes are not explicitly outlined in the search results, industrial suppliers like Hangzhou Lingrui Chemical Co., Ltd. and Dayang Chem (Hangzhou) Co., Ltd. in China specialize in its production, indicating scalable manufacturing processes24.

Applications

1. Pharmaceuticals and Biotechnology:

   • Potential use as an intermediate in drug synthesis or biochemical research, given its amino acid and phosphate functional groups215.

   • Suppliers like BIOZOL Diagnostica Vertrieb GmbH highlight its role in laboratory reagents and custom chemical solutions2.

2. Agriculture:

   • While not directly stated, structural analogs like glyphosate (a glycine-derived herbicide) suggest possible applications in agrochemical formulations, though further validation is needed13.

3. Industrial Chemistry:

   • Utilized as a specialty chemical in corrosion inhibition or polymer processing