Mannitol Factory Supply CAS 87-78-5

Basic Information

• Chemical Name: D - Mannitol.
• Molecular Formula:  C6​H14​O6​ .
• Molecular Weight: 182.17.

Physicochemical Properties

• Appearance: It is a white crystalline powder.
• Odor: Odorless.
• Taste: Sweet, with a sweetness about 0.5 - 0.7 times that of sucrose.
• Melting Point: 166 - 168℃.

Physiological Functions

• Dehydration: After intravenous injection of mannitol, because it is not easy to pass through the capillary wall into the tissue and can quickly increase the plasma osmotic pressure, the water in the interstitial fluid is transferred to the plasma, thus producing a tissue - dehydrating effect. It can reduce the intracranial pressure, intraocular pressure and the volume and pressure of cerebrospinal fluid.
• Diuretic Effect: After mannitol is filtered by the glomerulus, it is hardly reabsorbed by the renal tubules. It forms a high osmotic pressure in the renal tubules, preventing the reabsorption of water and producing an osmotic diuretic effect. At the same time, it can also dilate the renal blood vessels, increase the renal blood flow and further promote diuresis.

Industrial Applications

• Pharmaceutical Field: As a dehydrating agent, it is used to treat cerebral edema, glaucoma, etc.; as a diuretic, it is used to prevent and treat acute renal failure; it can also be used as a pharmaceutical excipient such as a diluent for tablets and a filler for capsules to improve the formability and stability of drugs.
• Food Field: It can be used as a sweetener in the food for diabetics and obese people, and it will not cause a rise in blood sugar. It can also be used as a humectant and thickener to improve the texture and taste of food and prolong the shelf life of food.
• Chemical Field: It is an important raw material for synthesizing chemical products such as mannitol fatty acid ester and mannitol epoxy resin. It can also be used in cosmetics as a humectant and conditioner, which has the effect of moisturizing and nourishing the skin.