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Human API 99% Rivaroxaban CAS 366789-02-8

10 Inquiries

Unit Price:

$185-240/G FOB

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CAS No.:

366789-02-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Brand:

HyperChem

Packaging:

vials,foil bag,drums

Price valid (until):

2026-09-30

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Rivaroxaban
CAS number	366789-02-8
Description	Rivaroxaban is a new oral anticoagulant. Due to its good anticoagulant effect, low risk of major bleeding, easy to take, and no need for routine monitoring, it has been widely used in the prevention and treatment of thrombosis in recent years.
Structural formula
Molecular Formula	C19H18ClN3O5S
Molecular Weight	435.88 g/mol
Appearance	White powder
Quality Standard	99%
Storage Condition	Inert atmosphere,2-8°C.
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Rivaroxaban More Info

Rivaroxaban (CAS No. 366789-02-8) is an innovative oral anticoagulant that directly inhibits Factor Xa, a key enzyme in the blood coagulation cascade. As a small molecule drug substance, it appears as a white to slightly yellowish powder with high purity and stability. This active pharmaceutical ingredient (API) is specifically designed for once-daily dosing due to its favorable pharmacokinetic profile, offering predictable anticoagulant effects without routine monitoring requirements. The compound is typically formulated into film-coated tablets for optimal patient administration.

Production Process

The manufacturing of rivaroxaban involves sophisticated synthetic organic chemistry processes conducted under strict GMP conditions. Production begins with carefully selected starting materials that undergo multiple synthetic steps, including chiral synthesis to ensure proper stereochemistry. The process includes rigorous purification stages such as crystallization and chromatography to achieve pharmaceutical-grade purity. Quality control laboratories employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, potency, and impurity profiles throughout production.

Applications and Market Position

As a leading direct oral anticoagulant (DOAC), rivaroxaban is clinically used for prevention of stroke in atrial fibrillation, treatment and prevention of venous thromboembolism, and post-surgical thromboprophylaxis. The global market for this API continues to expand, driven by its advantages over traditional anticoagulants and increasing prevalence of thromboembolic disorders. Major pharmaceutical companies worldwide incorporate rivaroxaban into their cardiovascular portfolios, with significant demand across North America, Europe, and emerging Asian markets.

Handling and Regulatory Compliance

Proper storage conditions for rivaroxaban include protection from moisture and maintenance at controlled room temperature in tightly sealed containers. Personnel should follow standard pharmaceutical handling procedures with appropriate personal protective equipment. Regulatory status varies by region, with approvals from major agencies including the FDA, EMA, and PMDA. Manufacturers must comply with current Good Manufacturing Practices and relevant pharmacopeial standards. Transportation should follow standard pharmaceutical material guidelines, and disposal must adhere to local environmental regulations for pharmaceutical substances.

FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express
FedEx UPS DHL EMS
Fast: 3-7 days around, high cost, door to door service

By Air
Suitable for more than 50kg
Fast: 3-7 days, hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Fast: 7-45 days, low cost, port to port, professional broker needed

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders:
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

Basic Info

Product Name:

Rivaroxaban

Other Name:

2-Thiophenecarboxamide,5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-;5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide;Rivaroxaban;BAY 59-7939;5-Chloro-N-[[(S)-3-(4-(3-oxomorpholin-4-yl)phenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]-thiophene-2-carboxamide;Xarelto;5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl]methyl]-2-thiophenecarboxamide;5-Chloro-N-([(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl]-methyl)-2-thiophenecarboxamide;(S)-Rivaroxaban;869880-21-7;931117-62-3;1807854-46-1

CAS No.:

366789-02-8

Molecular Formula:

C19H18ClN3O5S

InChIKeys:

InChIKey=KGFYHTZWPPHNLQ-AWEZNQCLSA-N

Molecular Weight:

435.88

Exact Mass:

435.88

EC Number:

1308068-626-2

UNII:

9NDF7JZ4M3

DSSTox ID:

DTXSID3057723

NCI Thesaurus Code:

C77995

Color/Form:

White to yellowish powder

ATC Code:

B01AF01|B - Blood and blood forming organs

Categories:

Antibiotics

Characteristics

PSA:

116

XLogP3:

2.5

Appearance:

Density:

1.5±0.1 g/cm3

Melting Point:

230 °C

Boiling Point:

732.6°C at 760 mmHg

Flash Point:

396.9±32.9 °C

Refractive Index:

1.633

Water Solubility:

Slightly soluble in organic solvents (e.g. acetone, polyethylene glycol 400) and is pratically insoluble in water and aqueous media

Storage Conditions:

Refrigerator

Vapor Pressure:

6.66X10-16 mm Hg at 25 deg C (est)

Odor:

Odorless

Henrys Law Constant:

Henry's Law constant = 9,46X10-85 atm-cu m/mol at 25 °C (est)

See More Rivaroxaban Properties 

Hazard Identification

Classification of the substance or mixture

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	No signal word
Hazard statement(s)	H411 Toxic to aquatic life with long lasting effects
Prevention	P273 Avoid release to the environment.
Response	P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Rivaroxaban Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

10 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Rivaroxaban	100.00 KG	Jan 8, 2026
India	Rivaroxaban	1.00 KG	Mar 8, 2026
Pakistan	Rivaroxaban	1.00 KG	Jan 23, 2026
India	Riveroxaban	1 MG	Dec 22, 2025
India	Nickel Oxide Sulphate	1.00 KG	May 11, 2026
India	Rivaroxaban	1.00 KG	Mar 18, 2026
India	Rivaroxaban	1.00 KG	Mar 11, 2026
India	Rivaroxaban	500.00 KG	Feb 2, 2026
India	Rivoraxaban IP	10.00 KG	Jan 22, 2026
India	Rivaroxaban	15 KG	Jul 29, 2025

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