Neocuproine 484-11-7

Focusing on innovative research, development, and production in the field of fine chemicals, we prioritize technology, quality, and market orientation. We collaborate with global partners to build a high-tech chemical industry chain and promote sustainable development in the industry.

The company's main products include pharmaceutical intermediates, food additives, essence, spices and plant extracts. The products have passed international certification and are exported to Europe, America, Japan, South Korea and Southeast Asia.

Neocuproine Basic information Product Name: Neocuproine Synonyms: TIMTEC-BB SBB008718;NEOCUPROINE REAG;NEOCUPROINE;10-Phenanthroline,2,9-dimethyl-1;2,9-dimethyl-10-phenanthroline;2,9-Dimethyl-o-phenanthroline;2,9-Dimethylphenanthroline;2,9 DiMethy 1,10-phenanthrofine CAS: 484-11-7 MF: C14H12N2 MW: 208.26 EINECS: 207-601-9 Product Categories: Analytical Chemistry;Chelating Reagents;Phenanthrolines;MOFS COFS;1 Mol File: 484-11-7.mol Neocuproine Chemical Properties Melting point  159-164 °C Boiling point  337.46°C (rough estimate) bulk density 280kg/m3 density  1.1345 (rough estimate) refractive index  1.6152 (estimate) RTECS  SF8380000 storage temp.  Keep in dark place,Sealed in dry,Room Temperature solubility  methanol: 0.1 g/mL, clear pka 6.01±0.30(Predicted) form  crystalline color  white to beige Water Solubility  slightly soluble Sensitive  Light Sensitive Merck  6449 InChIKey IYRGXJIJGHOCFS-UHFFFAOYSA-N CAS DataBase Reference 484-11-7(CAS DataBase Reference) NIST Chemistry Reference 1,10-Phenanthroline, 2,9-dimethyl-(484-11-7) EPA Substance Registry System 1,10-Phenanthroline, 2,9-dimethyl- (484-11-7) Safety Information Hazard Codes  Xi,Xn Risk Statements  36/37/38-20/21/22-22 Safety Statements  26-36/37/39-36-24/25 WGK Germany  3 TSCA  Yes HS Code  29339990 Neocuproine Usage And Synthesis Chemical Properties Neocuproine is a off-white to very pale yellow crystalline powder, in the presence of reducing agents it reacts with copper to give a copper(I) complex of composition MA2 and of tetrahedral symmetry. Uses Due to the steric hindrance of the methyl groups attached to the carbon atoms adjacent to the nitrogen donor atoms of phenanthroline, the reagent does not give the low spin vivid red complex characteristic of phenanthroline derivatives with iron(II). However, in the presence of reducing agents it reacts with copper to give a copper(I) complex of composition MA2 and of tetrahedral symmetry. This chelate is insoluble in water and can be extracted by chloroform in which the absorption maximum of the complex appears at 457 nm. In this way the concentration of the complex can be measured. The method is suitable for the determination of copper in iron, manganese and vanadium ores even in the presence of aluminium, germanium, titanium and silicon. Neocuproine is today considered one of the most selective reagents. Unfortunately, it is rather expensive. 2,3-bis-(2-pyridyl)quinoxaline, prepared by Belcher et al. by condensation of o-diketone, 2,2'-dipyridyl and 0-phenylenediamine(44) contains the functional grouping characteristic of cuproine; it is quite suitable for the determination of copper and it is cheap. Starting with various substituted o-phenylene-diamines Belcher synthesized 25 different quinoxaline derivatives, of which 2,3-bis-[2-(-methyl)-pyridyl)]quinoxaline proved to be identical with neocuproine as regards analytical selectivity. Besides copper, titanium(III) is the only metal ion which gives a colour reaction with the reagent. However, the coloured titanium(III) complex is formed only at lower pH and hence it does not interfere with the determination of copper. The copper complex of the reagent can be extracted quantitatively with isopentyl alcohol usually as a perchlorate ion pair. Uses Neocuproine is a phenanthroline based metal ion chelating agent. Definition ChEBI: A member of the class of phenanthrolines that is 1,10-phenanthroline bearing two methyl substituents at positions 2 and 9. Purification Methods Purifiy it as the hemihydrate by crystallisation from water and as the anhydrous base from *benzene. [Beilstein 23/8 V 527.] Neocuproine Preparation Products And Raw materials Raw materials Copper(1+)bis(2,9-diMethyl- 1,10-phenanthroline-->Ethenamine, 2,2'-(2,3-dinitro-1,4-phenylene)bis[N,N-dimethyl-, (E,E)- (9CI)-->1,4-dimethyl-2,3-dinitrobenzene-->8-Aminoquinaldine-->Ethyl vinyl ether Preparation Products 2,2'-Bipyridine-->1,10-PHENANTHROLINE-2,9-DICARBOXYLIC ACID-->1,10-Phenanthroline, 2,9-bis(bromomethyl)-



——  Q&A  ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.