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2,4-Difluoronitrobenzene 446-35-5

Name: 2,4-Difluoronitrobenzene 446-35-5
Brand: Orient
SKU: pr2511281648
Price: 4 USD
Availability: InStock

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CAS No.:

446-35-5

Grade:

Industrail Grade

Content:

99%

Port:

shanghai

Brand:

Orient

Packaging:

25L, 200L, 1000L, customized

Price valid (until):

2025-12-28

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

2,4-Difluoronitrobenzene Basic information

Synthesis

Product Name:	2,4-Difluoronitrobenzene
Synonyms:	1,3-difluoro-4-nitrobenzene;1-Nitro-2,4-difluorobenzene;2,4-difluoro-1-nitro-benzen;2,4-Difluronitrobenzene;Benzene, 2,4-difluoro-1-nitro-;2,4-DIFLUORO-1-NITROBENZENE;2,4-DIFLUORONITROBENZENE;2,4-DIFLUORO NITROBENZEN
CAS:	446-35-5
MF:	C6H3F2NO2
MW:	159.09
EINECS:	207-167-0
Product Categories:	Fluorine series;alkyl Fluorine\| nitro-compound;HALIDE;Aromatic Hydrocarbons (substituted) & Derivatives
Mol File:	446-35-5.mol

2,4-Difluoronitrobenzene Chemical Properties

Melting point	9-10 °C (lit.)
Boiling point	203-204 °C (lit.)
density	1.451 g/mL at 25 °C (lit.)
vapor density	>1 (vs air)
refractive index	n20/D 1.511(lit.)
Fp	195 °F
storage temp.	Sealed in dry,Room Temperature
form	clear liquid
color	Light yellow to Brown
Specific Gravity	1.45
Water Solubility	Insoluble in water.
BRN	2048034
Stability:	Stable. Incompatible with strong bases, strong oxidizing agents. Combustible.
InChIKey	RJXOVESYJFXCGI-UHFFFAOYSA-N
CAS DataBase Reference	446-35-5(CAS DataBase Reference)
NIST Chemistry Reference	2,4-Difluoronitrobenzene(446-35-5)
EPA Substance Registry System	2,4-Difluoronitrobenzene (446-35-5)

Safety Information

Hazard Codes	T,Xi,Xn
Risk Statements	25-36/37/38-23/24/25-20/21/22
Safety Statements	26-45-36/37/39-23
RIDADR	UN 2810 6.1/PG 1
WGK Germany	3
RTECS	CZ5730000
Hazard Note	Irritant
TSCA	T
HazardClass	6.1
PackingGroup	III
HS Code	29049090

2,4-Difluoronitrobenzene Usage And Synthesis

Synthesis	KF with n-Hexadecyltrimethylammonium bromide as the PTC has been shown recently to work in dimethylformamide (DMF), important owing to the low cost16 of DMF.
Chemical Properties	yellow liquid
Uses	2,4-Difluoronitrobenzene has been used in the synthesis of: 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction; (±)-horsfiline; resin-bound 2-arylaminobenzimidazoles. 2,?4-?Difluoronitrobenzene is a reactant in the preparation of 4-?thiazolidinone derivatives as antimicrobial agents.
Uses	2,4-Difluoronitrobenzene has been used in the synthesis of 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction, (±)-horsfiline and resin-bound-2-arylaminobenzimidazoles.
Uses	2,4-Difluoronitrobenzene has been used in the synthesis of: 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction (±)-horsfiline resin-bound 2-arylaminobenzimidazoles
General Description	Nucleophilic aromatic substitution of 2,4-difluoronitrobenzene with morpholine has been investigated using flow reactor with simulated moving bed (SMB) chromatography module.
References	[1] Catalysis Today, 2012, vol. 198, # 1, p. 300 - 304 [2] Patent: US2009/99387, 2009, A1. Location in patent: Page/Page column 8 [3] Patent: US2009/99387, 2009, A1. Location in patent: Page/Page column 7-9 [4] Tetrahedron, 1995, vol. 51, # 22, p. 6363 - 6376 [5] Journal of the American Chemical Society, 1956, vol. 78, p. 6034,6037

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

2,4-Difluoronitrobenzene

Other Name:

Benzene,2,4-difluoro-1-nitro-;2,4-Difluoro-1-nitrobenzene;1,3-Difluoro-4-nitrobenzene;2,4-Difluoronitrobenzene;1-Nitro-2,4-difluorobenzene;NSC 10259;1,5-Difluoro-2-nitrobenzene

CAS No.:

446-35-5

Molecular Formula:

C6H3F2NO2

InChIKeys:

InChIKey=RJXOVESYJFXCGI-UHFFFAOYSA-N

Molecular Weight:

159.09

Exact Mass:

159.09

BRN:

2048034

EC Number:

207-167-0

UNII:

6398Y1D7JS

NSC Number:

10259

DSSTox ID:

DTXSID0032869

HScode:

29049090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

45.8

XLogP3:

1.8

Appearance:

clear to yellowish liquid

Density:

1.5±0.1 g/cm3

Melting Point:

9.8 °C

Boiling Point:

207 °C

Flash Point:

195 °F

Refractive Index:

1.510

Water Solubility:

Insoluble in water.

Storage Conditions:

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Vapor Pressure:

0.331mmHg at 25°C

Vapor Density:

>1 (vs air)

See More 2,4-Difluoronitrobenzene Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell.
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 2,4-Difluoronitrobenzene Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	2,4 Difluoronitrobenzene	20.00 MT	May 30, 2024
India	2,4,DI FLURO NITRO BENZENE	1000.00 KG	Feb 13, 2025

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