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4-Morpholineethanesulfonic acid CAS:4432-31-9

Name: 4-Morpholineethanesulfonic acid CAS:4432-31-9
Brand: Orient
SKU: pr2511301021
Price: 4 USD
Availability: InStock

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CAS No.:

4432-31-9

Grade:

Industrial Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

25kg/bag,500kg/bag, customized

Price valid (until):

2025-12-30

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

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Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

4-Morpholineethanesulfonic acid Basic information

Application

Product Name:	4-Morpholineethanesulfonic acid
Synonyms:	MES 2-Morpholinoethanesulfonic acid;MES(2-(n-Morpholino)-ethanesulfonic acid), Free Acid;BBS13;FLJ20345;MKS1;ANTI-ME1 antibody produced in mouse;HUMNDME;ME1
CAS:	4432-31-9
MF:	C6H13NO4S
MW:	195.24
EINECS:	224-632-3
Product Categories:	buffer;Pharmaceutical Raw Materials;Biochemistry;Good's Buffers;Biotechnology Performance Certified (BPC) BuffersBiological Buffers;Buffer Convenience Packaging;Buffer SolutionsBiological Buffers;Buffers A to ZBiological Buffers;Good Buffers;BioUltraBiological Buffers;Buffer SolutionsProtein Structural Analysis;AlphabeticalMolecular Biology;Biological Buffers;BioUltra Buffers;Molecular Biology Reagents;Optimization Reagents;X-Ray Crystallography;4432-31-9
Mol File:	4432-31-9.mol

4-Morpholineethanesulfonic acid Chemical Properties

Melting point	>300 °C(lit.)
Boiling point	102°C
density	1.208 (estimate)
refractive index	1.5500 (estimate)
storage temp.	2-8°C
solubility	H₂O: 0.5 M at 20 °C, clear
pka	pKa at 0.1M ionic: 0°, 6.38; 20°, 6.15; 37°, 5.98; pKa1 1.99; pKa2 6.21; pKa/°C -0.011
form	Powder
color	White
PH	2.5-4.0 (25℃ in neat)
PH Range	5.5 - 6.7
Water Solubility	185.2g/L at 20℃
λmax	λ: 260 nm Amax: 0.01 λ: 280 nm Amax: 0.01
Merck	13,5929
BRN	6350956
Stability:	Stable. Incompatible with strong oxidizing agents.
InChIKey	SXGZJKUKBWWHRA-UHFFFAOYSA-N
LogP	-2.2 at 20℃
CAS DataBase Reference	4432-31-9(CAS DataBase Reference)
EPA Substance Registry System	4-Morpholineethanesulfonic acid (4432-31-9)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-24/25-22
WGK Germany	1
RTECS	QE9104530
HS Code	29349990

4-Morpholineethanesulfonic acid Usage And Synthesis

Application	4-Morpholineethanesulfonic acid (MES) is one of the good′s buffers, and the most extensively application is biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring and it does not form complexes with the majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes. MES has been also used as a component of the elution buffer used to elute plasma from α2-macroglobulin affinity column. It has been used as an activation buffer during antibody conjugation to microparticles and it has been used in the functionalization of microchannels during the creation of microfluidic-integrated surface plasmon resonance (SPR) platform for pathogen detection.
Chemical Properties	White/clear crystalline powder
Uses	Biological buffer.
Uses	MES solution has been used to activate microspheres. It has also been used as a component of activating solution to activate carboxyl groups of poly lactic-co-glycolic acid (PLGA).
Definition	ChEBI: 2-(N-morpholino)ethanesulfonic acid is a Good's buffer substance, pKa = 6.15 at 20 ℃. It is an organosulfonic acid and a MES. It is a conjugate acid of a 2-(N-morpholino)ethanesulfonate. It is a tautomer of a 2-(N-morpholiniumyl)ethanesulfonate.
General Description	MES is one of the Good′s buffers, the most extensively used biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring. It does not form complexes with majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes.
Flammability and Explosibility	Not classified
storage	Store at RT
Purification Methods	Crystallise MES from hot EtOH containing a little water. The picrate crystallises from EtOH and has m 178.8-182o. [Malkiel & Mason J Org Chem 8 199 1943, Beilstein 27 III/IV 370.]

4-Morpholineethanesulfonic acid Preparation Products And Raw materials

Raw materials	Sodium sulfite-->Sodium hypochlorite-->Sulfur trioxide-->LARD-->METHYL LAURATE-->Methyl palmitate
Preparation Products	2-Morpholin-4-yl-ethanesulfonyl chloride

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

4-Morpholineethanesulfonic acid

Other Name:

4-Morpholineethanesulfonic acid;MES;2-Morpholinoethanesulfonic acid;2-(N-Morpholino)ethanesulfonic acid;MES (buffering agent);2-(4-Morpholinyl)ethanesulfonic acid;Morpholinoethanesulfonic acid;2-(4-Morpholino)ethanesulfonic acid;NSC 157116;MES buffer;2-(Morpholin-4-yl)ethane-1-sulfonic acid;2-Morpholin-4-ium-4-ylethanesulfonate

CAS No.:

4432-31-9

Molecular Formula:

C6H13NO4S

InChIKeys:

InChIKey=SXGZJKUKBWWHRA-UHFFFAOYSA-N

Molecular Weight:

195.23700

Exact Mass:

195.24

EC Number:

224-632-3

UNII:

2GNK67Q0C4

NSC Number:

157116

DSSTox ID:

DTXSID4063454

HScode:

29349990

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

75.22000

XLogP3:

-3.5

Appearance:

white crystalline powder

Density:

1.349 g/cm3

Melting Point:

277-280 °C (decomp)

Refractive Index:

1.525

Water Solubility:

H2O: 0.5 M at 20 °C, clear

Storage Conditions:

Store at RT.

See More 4-Morpholineethanesulfonic acid Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 4-Morpholineethanesulfonic acid Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

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We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
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Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Switzerland	MES acide 2-(N-morpholino)éthanesulfonique,	100 G	Oct 31, 2025

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4-Morpholineethanesulfonic acid CAS:4432-31-9

Product Description

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