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(R)-(-)-2-Chloromandelic acid 52950-18-2

Name: (R)-(-)-2-Chloromandelic acid 52950-18-2
Brand: Orient
SKU: pr2512251070
Price: 4 USD
Availability: InStock

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CAS No.:

52950-18-2

Grade:

Industrail Grade

Content:

99%

Port:

shanghai

Brand:

Orient

Packaging:

1KG, 5KG, 25KG

Price valid (until):

2026-01-25

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Name:	(R)-(-)-2-Chloromandelic acid
Synonyms:	2-CHLORO-D-MANDELIC ACID;2-CHLORO-MANDELIC ACID (R);(R)-(2-CHLORO-PHENYL)-HYDROXY-ACETIC ACID;(R)-(-)-2-CHLOROMANDELIC ACID;(R)-2-CHLOROMANDELIC ACID;(R)-2-CHLORO-ALPHA-HYDROXYPHENYLACETIC ACID;(R-chloromandelicacid);(R)-ORTHO-CHLOROMANDELIC ACID
CAS:	52950-18-2
MF:	C8H7ClO3
MW:	186.59
EINECS:	444-040-0
Product Categories:	FINE Chemical & INTERMEDIATES;Carboxylic Acids;chiral;API intermediates;Chiral Building Blocks;Organic Building Blocks
Mol File:	52950-18-2.mol

(R)-(-)-2-Chloromandelic acid Chemical Properties

Melting point	119-121 °C(lit.)
alpha	-125 º (c=3, H2O)
Boiling point	266.91°C (rough estimate)
density	1.48
vapor pressure	0Pa at 25℃
refractive index	-124.5 ° (C=3, H2O)
storage temp.	Sealed in dry,Room Temperature
solubility	Methanol
pka	3.30±0.10(Predicted)
form	Solid
color	Off-White
Optical Rotation	[α]23/D 126°, c = 3 in H2O
BRN	2693370
LogP	1.51 at 23℃
Surface tension	48.7mN/m at 1g/L and 20℃
CAS DataBase Reference	52950-18-2(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,C
Risk Statements	36/37/38-43-41
Safety Statements	37/39-26-24/25-36-36/37/39
WGK Germany	3
HS Code	29181990

MSDS Information

(R)-(-)-2-Chloromandelic acid Usage And Synthesis

Chemical Properties	white to light yellow crystal powder
Uses	Clopidogrel intermediate.
Synthesis	74-90-8 89-98-5 10421-85-9 52923-20-3 First, 150 mL of toluene was added to a flask equipped with a stirrer and an internal thermometer. Under constant stirring, 0.09 g (0.08 x 10^-3 mol) of the (R,R)-VO salen complex of Example 1 and 21.1 g (0.15 mol) of freshly prepared 2-chlorobenzaldehyde were added sequentially. Subsequently, 10.1 g (0.375 mol) of hydrocyanic acid was added all at once. The resulting dark green homogeneous solution was stirred for 24 h at room temperature in a closed apparatus. The conversion was analyzed by gas chromatography (GC) to be 98% and the enantiomeric excess (ee) value of (S)-2-chloromandelate cyanohydrin was 73%.

First aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak. Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

(-)-2-Chloromandelic acid

Other Name:

Benzeneacetic acid,2-chloro-α-hydroxy-,(αR)-;Benzeneacetic acid,2-chloro-α-hydroxy-,(R)-;(αR)-2-Chloro-α-hydroxybenzeneacetic acid;(R)-2-Hydroxy-2-(2-chlorophenyl)acetic acid;(R)-2-Chloromandelic acid;(R)-(-)-2-Hydroxy-2-(2-chlorophenyl)acetic acid;(R)-(2-Chlorophenyl)(hydroxy)acetic acid;(R)-2-(2-Chlorophenyl)-2-hydroxyethanoic acid;(R)-o-Chloromandelic acid;(2R)-2-(2-Chlorophenyl)-2-(hydroxy)acetic acid;(-)-2-Chloromandelic acid;(R)-(-)-2-Chloromandelic Acid;(R)-2-(2-Chlorophenyl)-2-hydroxyacetic acid;1268686-44-7

CAS No.:

52950-18-2

Molecular Formula:

C8H7ClO3

InChIKeys:

InChIKey=RWOLDZZTBNYTMS-SSDOTTSWSA-N

Molecular Weight:

186.59200

Exact Mass:

186.59

EC Number:

444-040-0|610-917-3

DSSTox ID:

DTXSID10369958

HScode:

2918199090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

57.53000

XLogP3:

1.45800

Appearance:

white to light yellow crystal powder

Density:

1.48

Melting Point:

119-121ºC

Boiling Point:

350.3ºC at 760 mmHg

Flash Point:

165.7ºC

Refractive Index:

-124.5 ° (C=3, H2O)

See More (-)-2-Chloromandelic acid Properties 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	(R)-(-)-2-Chloromandelic acid	100 KG	Dec 24, 2025

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(R)-(-)-2-Chloromandelic acid 52950-18-2

Product Description

Seller Information

Inquiry History

First aid measures

Accidental release measures

Personal precautions, protective equipment and emergency procedures

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