High Purity Calcium Phosphate Dibasic CAS:7757-93-9 | Food/Feed/Pharma Grade Raw Material

Calcium phosphate dibasic More Info

Calcium phosphate dibasic, commonly referred to as dicalcium phosphate, is an inorganic compound with the chemical formula CaHPO₄, assigned the CAS Registry Number 7757-93-9. Its molecular structure consists of calcium cations and hydrogen phosphate anions arranged in a crystalline lattice. It is frequently encountered in hydrated forms, with the dihydrate being the most prevalent and stable under ambient conditions. This compound appears as a white, odorless, tasteless powder that is practically insoluble in water but soluble in dilute acids.

The primary function of dicalcium phosphate is as a source of two essential minerals: calcium and phosphorus. In biological systems, these ions are critical for building and maintaining bone and tooth structure, where they exist primarily in the form of hydroxyapatite. Beyond its nutritional role, DCP serves as a benign filler and abrasive agent in various industrial applications. Its chemical and physical stability makes it suitable for long-term formulation use in products where reactivity must be minimized.

This compound has extensive applications across several key industries. In nutrition, it is a major ingredient in dietary supplements, food fortification (e.g., in cereals and flours), and animal feed to ensure adequate mineral intake. In pharmaceuticals, it is widely used as an inert excipient in tablet and capsule formulations, where it acts as a diluent to provide bulk and improve powder flow during manufacturing. Industrially, it serves as a leavening agent in baking powder, a polishing agent in some toothpastes, and a raw material in producing other phosphorus compounds.

From a material science and processing perspective, dicalcium phosphate is valued for its consistent physical properties, such as compressibility and flowability, which are critical for high-speed tablet pressing. Different grades are manufactured to control particle size, density, and hydration state (anhydrous vs. dihydrate) to meet specific functional requirements in food or pharmaceutical processing. The dihydrate form is often preferred for direct compression tableting due to its superior handling characteristics.

The safety profile of dicalcium phosphate is excellent, underpinning its widespread use. It is generally recognized as safe by food and drug regulatory authorities worldwide. As a naturally occurring mineral and essential nutrient, it is biocompatible and non-toxic at intended levels of consumption. Excessive intake can theoretically contribute to hypercalcemia or hyperphosphatemia, but this is extremely unlikely from fortified foods or supplements under normal use. Its primary safety considerations in manufacturing involve controlling dust to avoid inhalation, as with any fine powder, but it presents no significant chemical hazards.

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