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• ⭐2-Cyanophenol (CAS 611-20-1), is an aromatic nitrile compound containing an aromatic ring, a hydroxyl group and a cyano group. Its molecular formula is C₇H₅NO, molecular weight is 119.12. In its molecular structure, the hydroxyl group (-OH) and cyano group (-CN) are located at the ortho-position of the benzene ring. This unique substituent arrangement endows it with both the active hydrogen characteristics of phenolic compounds and the nucleophilic reactivity of nitrile compounds, resulting in high chemical activity. It serves as an important bifunctional synthetic intermediate in the fine chemical industry and is widely applied in the chain synthesis of high-value-added products.
  
  
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• Item	Details
  CAS Number	611-20-1
  Names	2-Cyanophenol
  Appearance	White Powder

Ⅱ.Core Applications

1. 1 Pesticide Field: Core Raw Material for Methoxyacrylate Fungicides

   
   
   Application Products: Azoxystrobin, a world-leading high-efficiency, broad-spectrum and low-toxicity fungicide, widely used in the prevention and control of fungal diseases in various crops such as rice, wheat, corn, cotton, vegetables and fruits.

   
   

   Mechanism of Action: As a key precursor of the "benzene ring-heterocycle" structure in the azoxystrobin molecule, this product constructs the core active skeleton of azoxystrobin through condensation reaction with substituted phenoxyacetone, hydroxylamine and other raw materials. Its purity directly affects the yield of the condensation reaction (the synthetic yield corresponding to industrial-grade products is about 85-90%, while that of reagent-grade products can be increased to over 92%).

   
   

   Application Value: Azoxystrobin exerts its fungicidal effect by inhibiting the mitochondrial respiration of fungi, and has protective, curative and eradicative effects on dozens of fungal diseases such as rice blast, powdery mildew and downy mildew. The stable supply of 2-hydroxybenzonitrile is the core guarantee for the industrial production of such pesticides, helping to improve the quality and efficiency of agricultural production.
   
   

   2 Pharmaceutical Field: Intermediate for Cardiovascular Drugs

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   Application Products: a clinically commonly used non-selective β-receptor blocker with weak α-receptor blocking activity.

   
   

   Mechanism of Action: In the synthesis of this pharmaceutical product, 2-hydroxybenzonitrile introduces the o-hydroxyphenyl structure through ring-opening and amination reactions with relevant raw materials. This structure is the key pharmacophore for bunolol to bind to β-receptors, directly affecting the bioavailability and pharmacological activity of the drug.

   
   

   Application Value: Bunolol is mainly used clinically in the treatment of hypertension, angina pectoris, arrhythmia, glaucoma and other diseases, with stable antihypertensive effect and few side effects. The high purity and reaction selectivity of 2-hydroxybenzonitrile are important prerequisites for ensuring the quality and safety of bunolol.
   
   

   3 Fine Chemical Field: Intermediate for Functional Materials & Fragrance Synthesis

   
   
   Liquid Crystal Materials Direction: The aromatic ring structure of 2-hydroxybenzonitrile has good rigidity. The hydroxyl and cyano groups can act as hydrogen bond donors and acceptors between molecules, participating in the self-assembly and arrangement of liquid crystal molecules. By condensing with other liquid crystal mesogens (such as relevant aromatic and ester structures), liquid crystal materials with specific phase transition temperature and response speed can be prepared, which are applied in liquid crystal displays, liquid crystal sensors and other electronic devices to improve the display clarity and stability of the devices.

   
   

   Fragrance Synthesis Direction: 2-hydroxybenzonitrile can be converted into aromatic compounds with floral and fruity characteristics (such as o-hydroxybenzoate esters and o-hydroxybenzyl alcohol derivatives) through multi-step reactions such as hydrolysis, esterification and reduction. These compounds have fresh and long-lasting aromas, and can be used in the preparation of perfumes, essences, cosmetic fragrances and food additives, enriching the fragrance types of fragrance products.
   
   

   4 Other Application Fields

   
   
   Organic Synthetic Reagent: Used in the construction of heterocyclic compounds and modification of aromatic molecular structures in laboratory organic synthesis reactions.

   
   

   Dye Intermediate: Introducing different chromophores through substitution reactions to synthesize dyes with specific colors, applied in textile, printing and other industries.

   
   

   Corrosion Inhibitor Raw Material: Its hydroxyl and cyano groups can form an adsorption film on the metal surface to inhibit metal corrosion, suitable for the corrosion protection of industrial equipment and pipelines.
   
   
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Ⅲ.Packaging & Shipping

• Packaging Options: 1kg aluminum foil bag, 25kg kraft paper drum (customized packaging available)
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• Shipping Methods: DHL, FedEx, UPS, Sea Freight (global delivery supported)

• Payment Terms: T/T, USDT, BTC...

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• Ⅳ.FAQ
• Q: Can I get a free sample?
  A: Yes, free samples are available, and you only need to cover the shipping cost.
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• Q: Do you support OEM/ODM?
  A: Yes, we accept customized production for packaging, purity, and specifications.
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• Q: What is your MOQ?
  A: MOQ is [1kg] for most products, but we can also support small trial orders.
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• Q: How long is the delivery time?
  A: Usually 7-10 days for small orders, 15-20 days for bulk shipments.
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Ⅶ.Our Strength

• Professional Team

  
  

  We boast a highly seasoned international team composed of senior chemical engineers and elite supply chain experts. Our engineers, with years of hands-on experience in fine chemical R&D and production, are well-versed in the entire process from raw material selection, formula optimization and process parameter adjustment to strict quality control. Our supply chain specialists, equipped with a global perspective, excel in sourcing high-quality raw materials at competitive prices, optimizing logistics routes, and ensuring stable and on-time delivery to clients worldwide. This cross-functional team collaboration enables us to provide one-stop, customized solutions that perfectly meet diverse customer demands.
  
  
• Factory Capacity

  
  

  Our production base is equipped with state-of-the-art continuous crystallization and purification equipment, which ensures high production efficiency, stable product quality and low impurity levels for every batch of goods. With a large-scale production layout and automated production lines, we have achieved a substantial annual output to cater to both small-batch trial orders and large-volume bulk orders. The advanced production facilities not only guarantee the consistency of product purity and physical properties but also allow us to flexibly adjust production schedules according to market demand, ensuring favorable lead times even during peak seasons.
  
  
• Sustainable Focus

  
  

  We are firmly committed to promoting green chemistry and sustainable development throughout the entire production cycle. We have established long-term strategic partnerships with certified eco-friendly raw material manufacturers, strictly selecting raw materials that comply with international environmental standards to minimize the environmental footprint from the source. In the production process, we adopt energy-saving and emission-reduction technologies, optimize waste treatment procedures, and recycle reusable resources to achieve green production. Meanwhile, our packaging materials are chosen for their recyclability and environmental friendliness, further practicing our commitment to sustainability and meeting the eco-conscious requirements of global clients.
  
  
• After-Sale Service
  
  
  We provide comprehensive and efficient after-sales service to ensure a worry-free cooperation experience for every client. Our professional technical support team offers 7×24-hour uninterrupted service, ready to answer any technical questions about product application, storage conditions and process matching at any time. For quality-related inquiries, we implement a rapid response mechanism, with a dedicated team to follow up and provide detailed solutions in a timely manner. Additionally, we regularly conduct customer follow-up visits to collect feedback on product usage, continuously optimize product performance and service quality, and build long-term and stable cooperative relationships with clients based on mutual trust.