Sales manager:Amy
whatsapp/WeChat:+85296884746
Email:amy@yingliantech.cn
| Items | Specifications |
| Product Name | Retatrutide |
| CAS No | 2381089-83-2 |
| Molecular Weight | 4731.33 |
| Molecular Formula | C221H342N46O68 |
| Appearance | White Powder |
| Purity | ≥99.0% |
| Packaging | 5mg 10mg 15mg 20mg 30mg/vial 10vials/box |
Description
Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).
Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.
In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.
Indications and Efficacy
★ Obesity Treatment:
In the Phase II clinical trial, patients in the highest dose group (12 mg) lost an average of 24.2% weight after 48 weeks, and some patients lost more than 30%.
★ Metabolic Dysfunction-Associated Fatty Liver Disease (MASLD):
Retatrutide can reduce liver fat content by 86%, and more than 85% of patients achieve regression of liver steatosis.
★ Type 2 Diabetes:
Significantly reduce glycated hemoglobin (HbA1c) and improve blood sugar control.
★ Potential Cardiovascular Benefits:
Animal studies have shown that it may indirectly protect cardiovascular health by improving blood pressure and heart function, but further clinical verification is needed.
Storage Condition
Storage: Store at -20℃ degrees Celsius in a dry and cool place.
Storage Condition: Store at -20°C Solubility in DMSO: 3mg/mL (0.73 mM)
The storage conditions of Retatrutide vary depending on the form. The powder should be stored at − 20 ° C for 3 years and 4 ° C for 2 years. After dissolved in solvent, it should be stored at − 80 ° C for 6 months and at − 20 ° C for 1 month. In addition, Retatrutide should be refrigerated before opening, and can be kept refrigerated or stored at room temperature for 56 days after opening.
Transport
Company offers diverse shipping options: air, land, and sea transport. Orders are shipped within one day of placement, with delivery expected within a week. Boasting a high volume of successful transactions, we’ve earned strong trust from clients. Our efficient logistics ensure timely, reliable delivery, making us a dependable partner for your shipping needs.
Company Profile
Yinglian Technology Co., Ltd. (Jinzhou Hongbai Technology Co., Ltd. Subsidiary branch company)established in 2015, is a pioneering force in the biotechnology sector. At the core of our operations is the unwavering commitment to our guiding principles: "Quality First, Service Supreme."
Company Overview:
Founded in 2015 , our company has been a trailblazer in the field of biotechnology. We pride ourselves on our dedication to delivering cutting-edge products and unparalleled services.
Business Philosophy:
"Quality First, Service Supreme" encapsulates our business philosophy. We firmly believe that prioritizing quality in all aspects of our operations and providing exceptional service form the foundation for enduring success.
Key Products:
Our primary focus encompasses a range of products, including weight loss peptides, medicinal peptides, cosmetic peptides, and customized peptides. Notable among our weight loss peptide offerings are Semaglutide, Tirzepatide, Retatrutide, and others.
Mission:
Our mission is to spearhead advancements in biotechnology by consistently upholding the highest standards of quality and service. Through innovation and excellence, we aim to contribute to the betterment of global health and well-being.
Customized Peptides:
In addition to our standard product line, we specialize in crafting customized peptides tailored to meet the unique needs of our diverse clientele.
Future Vision:
As we move forward, yinglian technology is poised for continued growth and innovation. We are committed to expanding our product portfolio, staying at the forefront of technological advancements, and exceeding the expectations of our valued clients.
At Synpeptide Co., Ltd, we are not just shaping the future of biotechnology; we are pioneering a path towards a healthier and more sustainable world.
How to proceed your order:
Step 1:Please let me know the items you are favorable, quantities, and the destination country.
Step 2:You confirm all detail, and offer purchasing order.
Step 3:We send the detail price of our product and offer the suitable shipping method for reference.
Step 4:You confirm the order and payment 100% in advance and send us the detailed contacting information, including contacting person/company,address,mobile number,ZIP code and your special requirements.
Step5:We arrange the shipment according to your requirements, and tracking code will be offered once it is released, then you can track your parcel at any moment.
Step 6:We offer after-sales services after service after you receive your parcel.
Q1: Have your Product Quality been Approved by Third Party Lab?
Re: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China. So you will be assured with Good Quality if you choose us.
Q2: May I get one sample before placing order?
Re: Yes, Sample are available. For normal products, samples are for free and you just need to bear the freight; For those high value products, you just need to freight and certain product cost. When we both cooperate for some times or when you are our VIP customer, free sample will be offered when you need.
Q3: Which payment is available for your company?
Re: T/T, PayPal,bank transfer etc. You can choose the one which is convenient for you.
Q4: How and when can I get my goods after payment?
Re: For small quantity products, they will be delivered to you by international courier(DHL, FedEx, TNT etc.) or by air. Usually it will cost 5-7days that you can get the goods after delivery.For large quantity products, shipping by see is worthwhile.It will cost 15 to 30 days to come to your destination port, which depends on where the port is.
Q5: How about the price? Can you make it cheaper?
Re: We always take the customer's benefit as the top priority. Price is negotiable under different conditions, we are assuring you to get the most competitive price.
Q6:How to ensure the quality of your products?
From raw materials, production, processing, packaging, storage to shipment, we have carried out strict quality control .
Q7: Is there any possible to use my appointed label or package?
Re: Yes. If needed, we'd like.