Mazdutide (IBI362) is a gastrinoreceptor (OXM) agonist.
In terms of drug type, it belongs to the peptide class of drugs. This drug activates glucagon-like peptide - 1 receptor (GLP - 1R) and glucagon receptor (GCGR) and has multiple metabolic regulatory effects.
In terms of therapeutic applications, it is mainly used in the treatment of diseases such as type 2 diabetes and obesity. It reduces body weight by regulating appetite and energy metabolism while improving glycemic control. For example, in clinical trials, Mazdutide demonstrated favorable effects in lowering blood glucose levels and reducing patient weight.
Name | Mazdutide |
CAS RN | 2259884-03-0 |
Form | Powder |
EINECS | 884-103-0 |
Acts on the appetite regulation center of the brain to reduce food intake by increasing satiety. Patients will feel fuller more easily and thus spontaneously reduce the amount of food they eat to control calorie intake.
It can increase energy expenditure. It raises the body's basal metabolic rate, allowing the body to burn more calories even at rest, helping the user to lose weight, a role that is particularly important for obese or overweight patients with type 2 diabetes.
Some studies have suggested a possible protective effect on the cardiovascular system. This may be through a variety of mechanisms such as improving cardiovascular risk factors such as blood glucose, blood pressure, and lipids, as well as reducing body weight to reduce the risk of cardiovascular disease. However this function needs to be confirmed by more research and clinical trials.
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