High Purity KPV Tripeptide Raw Material CAS 67727-97-3

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——  KPV Product introduction CAS 67727-97-3   ——

KPV (CAS: 67727-97-3   ) is a high-purity tripeptide derived from α-MSH, developed for immunomodulatory and epithelial biology research. It selectively regulates inflammatory signaling, supports tissue barrier integrity, and aids in the study of inflammatory resolution and tissue repair mechanisms.
This bioactive ingredient suppresses key pro-inflammatory pathways and cytokines while maintaining immune homeostasis. It exhibits low immunogenicity and good stability, making it suitable for various preclinical studies in dermatology, mucosal health, and immunology.

At the molecular level, KPV functions as a selective modulator of inflammatory cascades, primarily targeting the NF-κB signaling pathway via PepT1-mediated cellular uptake. This mechanism enables it to suppress the production of major pro-inflammatory cytokines including TNF-α, IL-1β, and IL-6, while preserving the homeostatic balance of immune responses. Its unique structural properties confer low immunogenicity and enhanced stability in biological matrices, supporting consistent performance across diverse in vitro and ex vivo experimental systems.

——  KPV CAS 67727-97-3：Functions & Applications   ——

Functions：

KPV is a bioactive tripeptide with fundamental roles in immunomodulation, inflammatory signaling regulation, and epithelial tissue homeostasis. It modulates key cellular pathways to regulate inflammatory cascades, supporting balanced immune responses and redox equilibrium. By influencing pro-inflammatory cytokine production and signaling processes, it helps promote a stable tissue microenvironment, supporting epithelial barrier integrity and natural tissue defense responses. Widely investigated for its capacity to facilitate inflammatory resolution and maintain mucosal health, it represents a central focus in research exploring advanced biological wellness strategies. It aids in sustaining balanced tissue function, supporting long-term epithelial resilience and inflammatory homeostasis across extended biological timelines.

Application：

KPV is intended solely for laboratory and preclinical research purposes focused on immunomodulation, epithelial biology, and inflammatory-related studies. It serves as a core research tool for investigating biological pathways related to inflammation regulation, tissue repair, and mucosal maintenance. Researchers leverage its unique mechanism to explore innovative approaches to tissue health, particularly in preclinical work examining the biological drivers of epithelial integrity and inflammatory balance. It is widely adopted in academic and pharmaceutical research settings to advance understanding of peptide-based biological support, facilitating the development of novel frameworks for maintaining healthy tissue performance and immune function.

Should be stored in the refrigerator at 2°C to 8°C, away from light.

If required, each single-dose pen can be stored unrefrigerated at a temperature not exceeding 30°C for up to 21 days, but once stored at room temperature it should not be returned to the refrigerator. If not used within 21 days after removal from the refrigerator, it should be discarded. Do not freeze tilpotide and if frozen, do not use.

——   Company profile  ——

Our company is a high-tech enterprise specializing in the R&D, large-scale production, and global supply of active peptide raw materials. Focusing on pharmaceutical peptides, cosmetic peptides, nutritional health peptides, and research-grade peptides, we provide high-purity, compliant, and stable peptide products, as well as custom synthesis services for pharmaceuticals, cosmetics, functional foods, and life science research sectors.
Backed by proprietary core peptide synthesis and modification technologies, we have built an intelligent production system aligned with GMP standards, supported by a strict quality control and full-process traceability framework. Our products hold multiple international certifications and are exported to dozens of countries and regions worldwide.
Guided by technology-driven industrial upgrading and a customer-centric approach, we are committed to becoming a globally trusted provider of peptide raw material solutions, empowering the high-quality development of the health and beauty industries.

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