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Isocalamendiol

Name: Isocalamendiol
Brand: Cuicheng Bio
SKU: pr2606081157
Price: 200000 USD
Availability: InStock

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CAS No.:

25330-21-6

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Brand:

Cuicheng Bio

Packaging:

5mg

Price valid (until):

2026-07-08

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Product Description
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Description

Isocalamendiol (also spelled isocalamenediol) is a natural sesquiterpenoid compound containing a cadinane-type bicyclic core framework. Its primary functions span botanical chemical defense, ethnopharmacological therapeutic activity, and fragrance composition.

It is natively isolated from the essential oils and rhizomes of Acorus calamus L. (commonly known as Sweet Flag, Vacha) and certain aromatic plants in the Apiaceae family.

1. Core Biological and Pharmacological Functions

Because it is a key constituent of the volatile fraction of Acorus calamus roots, isocalamendiol is heavily studied for its contributions to the plant's overall multi-targeted therapeutic properties:

Gastrointestinal Spasmolytic & Antispasmodic Activity: Isocalamendiol functions as a smooth muscle relaxant. Pharmacological data suggests that volatile constituents in the Calamus rhizome can modulate calcium channels and exhibit anticholinergic profiles. This helps relieve internal stomach cramps, colic, and severe digestive spasms.
Antimicrobial and Antifungal Activity: The compound exhibits broad-spectrum antimicrobial properties. It functions to inhibit the growth of various pathogenic bacteria and opportunistic environmental fungi, bolstering the plant's defense system and serving as a baseline candidate for natural preservatives.
- Antioxidant Capabilities: Due to its sesquiterpenoid framework, it helps quench free radicals and downregulate localized oxidative stress, safeguarding lipid pathways and surrounding cellular matrices from damage. [1, 2, 3]
- Potential In Silico Anticarcinogenic Profiles: Emerging computational network pharmacology and molecular docking models indicate that isocalamendiol derivatives can stably bind to critical cellular signaling receptors, pointing to potential bioactive value in anti-cancer and anti-proliferative screening models (such as gastric cancer pathways).
2. Ecological and Commercial Functions
- Plant Chemical Defense Matrix: Within the rhizomes of Acorus calamus, isocalamendiol functions as a potent defensive secondary metabolite. It possesses natural insecticidal, larvicidal, and pesticidal properties designed to ward off soil-borne insects, parasites, and hungry herbivores.
- Fragrance and Perfumery Component: In industrial chemistry, isolated or synthetically derived isocalamendiol carries a distinct, warm, woody, and spicy aromatic odor profile. It is utilized in fine fragrance chemistry and cosmetics as an accent oil or stabilizer.
- Phytochemical Reference Standard: High-purity isocalamendiol is utilized in laboratory settings as a certified reference standard. It allows analysts to deploy gas chromatography-mass spectrometry (GC-MS) to accurately map, authenticate, and standardize the quality of commercial herbal extractions.

Basic Info

Product Name:

(1R,8aα)-Decahydro-1-methyl-6-methylene-4β-isopropyl-1α,4aβ-naphthalenediol

Other Name:

(1R,8aα)-Decahydro-1-methyl-6-methylene-4β-isopropyl-1α,4aβ-naphthalenediol;Isocalamendiol

CAS No.:

25330-21-6

Molecular Formula:

C15H26O2

InChIKeys:

AHNGXHRYFGQWSL-BYNSBNAKSA-N

Molecular Weight:

238.36574

Exact Mass:

238.193283

HScode:

2906199090

Categories:

Sesquiterpene

Characteristics

PSA:

40.46000

XLogP3:

3.34

Density:

1.0±0.1 g/cm3

Boiling Point:

342.2±42.0 °C at 760 mmHg

Flash Point:

153.3±22.5 °C

Refractive Index:

1.517

See More (1R,8aα)-Decahydro-1-methyl-6-methylene-4β-isopropyl-1α,4aβ-naphthalenediol Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More (1R,8aα)-Decahydro-1-methyl-6-methylene-4β-isopropyl-1α,4aβ-naphthalenediol Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2019
Country Product Purchase Quantity Date Posted

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Isocalamendiol

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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