SS-31 C32H49N9O5 ,736992-21-5, hot selling ,10mg etc,good price tb500 reta

SS-31 (also known as Elamipretide or MTP-131) is a synthetic mitochondrial-targeting tetrapeptide. Its core mechanism of action involves precisely targeting the inner mitochondrial membrane, stabilizing mitochondrial structure and function by protecting a key phospholipid—cardiolipin—thereby improving energy metabolism and reducing oxidative damage. 

Targeted binding to cardiolipin: It precisely binds to cardiolipin, a key phospholipid on the inner mitochondrial membrane. Cardiolipin is crucial for maintaining the structure and function of mitochondrial energy production (oxidative phosphorylation), and SS-31 stabilizes mitochondrial function by protecting it.

Action on key proteins: Studies have also found that it interacts with multiple mitochondrial proteins involved in ATP synthesis and metabolism, providing direct molecular evidence for its ability to improve mitochondrial energy metabolism.

• Improved Cardiac Function: In cardiomyopathy models such as Bartholin's syndrome, SS-31 improves cardiac mitochondrial respiration and supercomplex assembly. In heart failure models, it improves left ventricular function and mitochondrial function.

  Reduces Myocardial Injury: It can alleviate cardiomyocyte senescence induced by the chemotherapy drug doxorubicin. It also has a protective effect in myocardial ischemia-reperfusion injury models.

  Neuroprotection

  Promotes Spinal Cord Injury Repair: This is a current research hotspot. SS-31 has been shown to significantly improve motor function recovery in spinal cord injury models, through mechanisms including reducing neuronal apoptosis, protecting mitochondrial function, and promoting neural remodeling. One study also specifically noted that it can alleviate pathological changes in cardiolipin.

  Improved Cognitive Function: In neuroinflammation models, SS-31 shows the potential to improve memory impairment.

  Improved Age-Related Functions

  Anti-Osteoporosis: In a 2025 study, SS-31 was shown to significantly restore the osteogenic differentiation capacity of aging bone marrow mesenchymal stem cells, for example, increasing alkaline phosphatase (an osteogenic differentiation marker) activity by 2.8 times. Its mechanism involves restoring mitochondrial function by inhibiting NOS2 gene expression.

  It also delays cellular senescence: significantly improving the quality and maturation rate of oocytes in older mice.

Our company is a modern enterprise specializing in the research, development, production, and export of active pharmaceutical ingredients (APIs), pharmaceutical intermediates, and plant extracts. Our products are widely used in pharmaceutical preparations, health foods, cosmetics, dietary supplements, and food additives.

Our factory covers 105 acres and is built to GMP standards. It boasts a rational layout and excellent environment, with large and medium-sized production workshops and refining workshops, equipped with an advanced quality inspection center and R&D laboratory. Our products have reached advanced domestic levels in terms of quality and technology.

The company has long emphasized team building and technological improvement, employing modern production lines to ensure high-precision and high-efficiency production operations. From processing, extraction, and packaging to transportation, the entire process is completed in-house, ensuring quality and efficiency from the source. We are committed to the research and innovation of new raw materials and products, winning the trust and praise of customers both domestically and internationally.

Through years of development, the company has accumulated rich experience in international trade, established a comprehensive marketing service system, and a stable customer network. Furthermore, the company has established long-term technical cooperation relationships with experts and professors from several universities and research institutes in the province, continuously enhancing its comprehensive R&D capabilities.