 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > 17-Dimethylaminoethylamino-17-demethoxygeldanamycin for Sale > Alvespimycin powder,98%,dark purple

Alvespimycin powder,98%,dark purple

COA

Unit Price:

$700/G EXW

Get Latest Price 

CAS No.:

467214-20-6

Content:

98%

Packaging:

10g/bag

Price valid (until):

2026-08-16

Contact Supplier

 Chat Now

Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

 Visit Store

Product Description
Seller Information

Description

Efficacy and Applications of Acetylspiramycin

Acetylspiramycin (commonly referred to in clinical settings as Spiramycin Acetate) is a macrolide antibiotic. It primarily exerts its bacteriostatic or bactericidal effects by inhibiting bacterial protein synthesis, making it widely utilized in clinical medicine.

Its core efficacy and primary medical applications include:

I. Core Efficacy

Antibacterial Activity: It exhibits potent antibacterial performance against Gram-positive bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus pyogenes.
Targeting Specific Pathogens: It is highly effective against atypical pathogens such as Mycoplasma, Chlamydia, Cryptosporidium, and Toxoplasma gondii.
Excellent Tissue Penetration: Following oral administration, the drug achieves high concentrations in saliva, gingival tissue, tonsils, and respiratory glands, often exceeding its concentration in the bloodstream.

II. Primary Clinical Applications

Due to its unique tissue distribution profile, it is most commonly prescribed for mild-to-moderate infections in the following areas:

1. Oral and Maxillofacial Infections (Most Notable Application)

Because it concentrates heavily in saliva and gum tissues, it is frequently used as a first-line agent for periodontitis, pericoronitis, pulpitis, and buccal/facial infections.

2. Respiratory and ENT (Ear, Nose, Throat) Infections

It is used to treat infections caused by sensitive bacteria, such as pharyngitis, tonsillitis, acute bronchitis, pneumonia, otitis media, and sinusitis.

3. Skin and Soft Tissue Infections

It demonstrates clinical efficacy in treating folliculitis, furuncles (boils), pyoderma, scarlet fever, and erysipelas.

4. Special Parasitic Infections

Gynecology & Obstetrics: It is the drug of choice for treating toxoplasmosis in pregnant women, as it can cross the placental barrier to prevent vertical mother-to-child transmission.
It is also utilized to treat intestinal cryptosporidiosis.

III. Differentiation and Substitution vs. Amoxicillin

In daily life, this medication is frequently confused with amoxicillin. However, they differ in key ways:

Alternative for Penicillin Allergic Patients: Amoxicillin belongs to the penicillin class, a common allergen for many individuals. Since acetylspiramycin is a macrolide, it serves as a crucial alternative for patients allergic to penicillin.
Different Antibacterial Focus: While amoxicillin is a broad-spectrum antibiotic, acetylspiramycin offers superior tissue penetration in the oral cavity and target specificity against atypical pathogens (such as Mycoplasma and Toxoplasma).

⚠️ Important Medical Notice

Prescription Only: This medication is a strictly regulated prescription antibiotic. It must be taken under professional medical guidance; self-medication is strongly discouraged to prevent the development of bacterial resistance.
Ineffective Against Viruses: This drug is only active against bacteria and specific micro-pathogens; it is ineffective against sore throats caused by viruses like the common cold or influenza.
Administration Timing: Some patients may experience mild gastrointestinal discomfort, such as nausea or vomiting. Taking the medication after meals is recommended to minimize gastric irritation.
Avoid Dairy Products: To ensure optimal drug absorption, avoid taking the medication concurrently with dairy products (such as milk or cheese); a 2-hour window between consumption is recommended.

Items	Specifications
melting point	>270°C
boiling point	810.5±65.0 °C
storage condition	Desiccate at -20°C
solubility	DMSO (Slightly), Methanol (Slightly)
color and appearance	very dark purple solid

Certificates

Basic Info

Product Name:

17-Dimethylaminoethylamino-17-demethoxygeldanamycin

Other Name:

Geldanamycin,17-demethoxy-17-[[2-(dimethylamino)ethyl]amino]-;17-Demethoxy-17-[[2-(dimethylamino)ethyl]amino]geldanamycin;NSC 707545;17-DMAG;17-[2-(Dimethylamino)ethylamino]-17-desmethylgeldanamycin;DMAG;Alvespimycin;17-N-(2-Dimethylaminoethylamino)-17-demethoxygeldanamycin;17-Dimethylaminoethylamino-17-demethoxygeldanamycin

CAS No.:

467214-20-6

Molecular Formula:

C32H48N4O8

InChIKeys:

InChIKey=KUFRQPKVAWMTJO-LMZWQJSESA-N

Molecular Weight:

616.74552

Exact Mass:

616.75

HScode:

29419090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

169.52000

XLogP3:

2.07

Density:

1.2±0.1 g/cm3

Boiling Point:

810.5±65.0 °C at 760 mmHg

Flash Point:

444.0±34.3 °C

Refractive Index:

1.566

Water Solubility:

Soluble

Storage Conditions:

Desiccate at -20°C

See More 17-Dimethylaminoethylamino-17-demethoxygeldanamycin Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 17-Dimethylaminoethylamino-17-demethoxygeldanamycin Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2019
Country Product Purchase Quantity Date Posted

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Supplier Name	Details
Alvespimycin	/0.98	Creative Enzymes	Inquiry
Alvespimycin 99% white powder kanbei	Industrial Grade/99	Henan Lihao Chem Plant Limited	Inquiry
Alvespimycin	Industrial Grade/99	Shaanxi Cuikang Pharmaceutical Technolog	Inquiry
High-purity raw material Alvespimycin CAS 467214-20-6 at competitive pricing	Pharmaceutical Grade/99	Xi'an Honest BioEngr Co.,Ltd.	Inquiry