 Home > Encyclopedia > 2-Acetyl-5-methylthiophene

2-Acetyl-5-methylthiophene

2-Acetyl-5-methylthiophene structure

CAS No:
13679-74-8
Formula:
C7H8OS
Chemical Name:
2-Acetyl-5-methylthiophene
Synonyms:
Ethanone,1-(5-methyl-2-thienyl)-;Ketone,methyl 5-methyl-2-thienyl;1-(5-Methyl-2-thienyl)ethanone;Methyl 5-methyl-2-thienyl ketone;2-Acetyl-5-methylthiophene;2-Methyl-5-acetylthiophene;5-Methyl-2-thienyl methyl ketone;1-(5-Methylthiophen-2-yl)ethanone;1-(5-Methylthiophen-2-yl)ethan-1-one
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Request for Quotation

Description

white to light yellow crystal powder

Solid|Colourless to pale yellow liqud to crystalline powder at lower temperatures; Roasted aroma with sweet notes

2-Acetyl-5-methylthiophene is an aromatic ketone.

2-Acetyl-5-methylthiophene Basic Attributes

Molecular Weight：

140.2

Exact Mass：

140.20

BRN：

110854

EC Number：

237-181-2

UNII：

2HS3I278W9

DSSTox ID：

DTXSID10159932

HScode：

29349990

Characteristics

PSA：

45.3

XLogP3：

Appearance：

White to pale yellow Low Melting Crystalline Mass, Powder or Crystals

Density：

1.12 g/cm³ @ Temp: 25 °C

Melting Point：

27.5 °C

Boiling Point：

232.5 °C

Flash Point：

>230 °F

Refractive Index：

n20/D 1.561(lit.)

Water Solubility：

Very slightly soluble in water

Vapor Pressure：

0.0517mmHg at 25°C

Safety Information

Hazard category：

STENCH

Transport codes：

UN 3335

wgk germany：

hazard class code：

20/21/22

safety instructions：

36/37-22

RTECS Number：

OB4972000

Marks：

Xn,Xi

Hazard note：

Irritant

Precautionary statement(s)：

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (88.89%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 9 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

2-Acetyl-5-methylthiophene Use and Manufacturing

Methods of Manufacturing

General procedure: The Friedel-Crafts acylation of Anisole (1 g, 9.26 mmol)(Aldrich, 99.0percent) with propionyl chloride (5 equiv.)(Aldrich, 99.0percent) using the prepared MoO4(AlCl22(5 wtpercent, 10 mg) catalyst was carried out in a magneticallystirred two-necked round bottom flask fitted witha guard tube (CaCl2, activated at 150 C for 2 h. Thepresent reaction mixture stirred at room temperature up tothe completion of reaction. Reaction progress was monitoredby thin layer chromatography (TLC). After completionof the reaction, reaction mixture was filtered andsolid catalyst was separated out. The separated solid catalystcan be recycled in next attempt of Friedel-Craftsacylation reaction. The reaction mixture was washed withdichloromethane (DCM) and water, the same process wasdone triplicate and collected the organic layer. The organiclayer was then dried over anhydrous sodium sulfate andconcentrated on rotary evaporator and crude acylated productwas obtained and purified on column chromatography.EXAMPLE 7

Use Classification：

Flavouring Agent -> FLAVOURING_AGENT; -> JECFA Functional Classes|Flavoring Agents -> JECFA Flavorings Index

Food Additive Classes：

Flavouring Agent -> FLAVOURING_AGENT;|Flavoring Agents

Computed Properties

Molecular Weight:140.20
XLogP3:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:140.02958605
Monoisotopic Mass:140.02958605
Topological Polar Surface Area:45.3
Heavy Atom Count:9
Complexity:122
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 2-Acetyl-5-methylthiophene

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

2-Acetyl-5-methylthiophene

CAS No.: 13679-74-8

Content: 99.00%

Inquiry
Greenbo Biochem Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides,Organic Intermediates,OLED Intermediates

1-(5-Methyl-2-thienyl)ethan-1-one 99% high quality Professional thiofuran seires Producer Greenbo

CAS No.: 13679-74-8

Grade: Pharmaceutical Grade

Content: 99%

Inquiry

Latest News on 2-Acetyl-5-methylthiophene

Learn More Other Chemicals

(2E)-3-(1-METHYL-1H-PYRROL-2-YL)ACRYLIC ACID

51485-76-8
Benadryl N-oxide hydrochloride

13168-00-8
6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE

885275-59-2
(2-Bromophenyl)diphenylphosphine Formula

62336-24-7
1-Morpholinocyclopentene Formula

936-52-7
4-[2-(Boc-amino)ethoxy]-benzoic acid Formula

168892-66-8
3-amino-5-bromopyridine-2-carboxylic acid Structure

870997-85-6
2-Amino-6-methylpyridine Structure

1824-81-3
What is 3-Bromo-2-methylthiophene

30319-05-2
What is THIOPHEN-2-YLMETHYL-PHOSPHONICACIDDIETHYLESTER

2026-42-8

Hot Searches: naf compound name; methanethiol; copper sulphide; no2 chemical name; hexamethylenediamine; lacunar infarct symptoms

Guide of 2-Acetyl-5-methylthiophene

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
Learn More Other Chemicals

2-Acetyl-5-methylthiophene

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.