Deslanoside

This product is a sterile solution made of deacetylated lanolin and 10% ethanol. Molecular formula: C47H74O19 Molecular weight: 943.09

1. When used with amphotericin B, corticosteroids or potassium-losing diuretics such as bumetanide and ethacrynic acid, it can cause hypokalemia and lead to digitalis poisoning; 2. When used with ester-forming drugs (especially trisilicic acid) or antidiarrheal adsorbents such as white clay, gelatin, cholestyramine and other anion exchange resins, sulfasalazine or neomycin, and aminosalicylic acid, it can inhibit the absorption of pandipine cardiac glycosides and lead to a weakening of the effect of cardiac glycosides; 3. When used with antiarrhythmic drugs, calcium salt injections, cocaine 4. When pancuronium, rosin, succinylcholine or adrenomimetics are used together, arrhythmias may occur due to additive effects; 5. Pandiol sulphonation patients with severe or complete atrioventricular block and normal blood potassium should not use potassium salts at the same time, but potassium salts are often given when thiazide diuretics are used with this product to prevent hypokalemia; 6. When beta-blockers are used with this product, there is a possibility of severe bradycardia in atrioventricular block, which should be taken seriously. However, it does not rule out the use of beta-blockers for supraventricular tachyarrhythmias where digitalis cannot control the ventricular rate; 7. When used with quinidine, the blood concentration of this product can be increased by about one-fold, and the degree of increase is related to the dosage of quinidine, and can even reach a toxic concentration. Even if digoxin is discontinued, its blood concentration continues to rise. This is because quinidine replaces digoxin from tissue binding and reduces its distribution volume. When the two drugs are used together, the dosage of digoxin should be reduced by 1/2-1/3; 7 When used together with verapamil, diltiazem, and amiodarone, the blood concentration of digoxin will be increased due to reduced renal and systemic clearance, which may cause severe bradycardia; 8 Spironolactone can prolong the half-life of this drug, and the dose or dosing interval needs to be adjusted, and the blood concentration of this product should be followed up and monitored; 9 Angiotensin-converting enzyme inhibitors and their receptor antagonists can increase the blood concentration of this product; 10 Edrophonium chloride (Tensilon) and this product can cause obvious bradycardia. 11 Indomethacin (Indomethacin) can reduce the renal clearance of this product, prolonging its half-life and causing the risk of poisoning. Blood drug concentration and electrocardiogram should be monitored. 12 When used with heparin, this product may partially offset the anticoagulant effect of heparin, so the dosage of heparin needs to be adjusted. 13 When digitalizing, intravenous magnesium sulfate should be used with extreme caution, especially when calcium salts are also injected intravenously, as heart block may occur. 14 Erythromycin can increase the absorption of this product in the gastrointestinal tract by changing the gastrointestinal flora. 15 Metoclopramide (Maxolon) reduces the bioavailability of digoxin by about 25% due to promoting intestinal motility. Propane increases the bioavailability of digoxin by about 25% due to inhibiting intestinal peristalsis. 16 It is forbidden to be used with calcium injection. 17 It should not be used in combination with acids or bases.

This product is a sterile solution made of deacetylated lanolin and 10% ethanol. Molecular formula: C47H74O19 Molecular weight: 943.09

1. When used together with amphotericin B, corticosteroids or potassium-losing diuretics such as bumetanide (the product is buturamine) and ethacrynic acid (ethacrynic acid), it can cause hypokalemia and lead to digitalis poisoning; 2. When used together with antacids (especially magnesium trisilicate) or antidiarrheal adsorbents such as white clay, pectin, cholestyramine, and other anion exchange resins, sulfasalazine or neomycin, and para-aminosalicylic acid, it can inhibit the absorption of digitalis cardiac glycosides and lead to a weakening of the effect of cardiac glycosides; 3. When used together with antiarrhythmic drugs, calcium salts When injection, cocaine, pancuronium bromide (PancuroniumBromide, Pan Kelong, Bahuolang), rauwolfia alkaloids, succinylcholine (Sceline; SuxamethoniumChloride) or adrenergic drugs are used together, arrhythmias may occur due to additive effects; 4 Digitalized patients with severe or complete atrioventricular block and normal blood potassium should not use potassium salts at the same time, but when thiazide diuretics are used with this product, potassium salts are often required to prevent hypokalemia; 5 β-receptor blockers used with this product may cause severe bradycardia due to atrioventricular block, which should be taken seriously. However, it does not rule out the use of beta-blockers for supraventricular tachyarrhythmias where digitalis cannot control the ventricular rate; 6. When used together with quinidine, the blood concentration of this product can be increased by about one-fold. The degree of increase is related to the dosage of quinidine and can even reach toxic concentrations. Even if digoxin is discontinued, its blood concentration continues to rise. This is because quinidine replaces digoxin from tissue binding and reduces its distribution volume. When the two drugs are used together, the dosage of digoxin should be reduced by 1/2-1/3; 7 When used together with verapamil, diltiazem, and amiodarone, the blood concentration of digoxin can be increased due to the reduction of the renal and systemic clearance rate of digoxin, which can cause severe bradycardia; 8 Spironolactone can prolong the half-life of this product, and the dose or dosing interval needs to be adjusted, and the blood concentration of this product should be followed up and monitored; 9 Angiotensin converting enzyme inhibitors and their receptor antagonists can increase the blood concentration of this product; 10 EdrophoniumChloride (Tensilon) and this product can cause obvious bradycardia when used together; 11 Indomethacin (Indome 12. When used with heparin, the dosage of heparin should be adjusted because this product may partially offset the anticoagulant effect of heparin; 13. When using magnesium sulfate intravenously during digitalization, extreme caution should be exercised, especially when calcium salts are also injected intravenously, as heart block may occur; 14. Erythromycin can increase the absorption of this product in the gastrointestinal tract by changing the gastrointestinal flora; 15. Metoclopramide (Maxolon) reduces the bioavailability of digoxin by about 25% due to promoting intestinal motility. Propane increases the bioavailability of digoxin by about 25% due to inhibiting intestinal peristalsis; 16. It is forbidden to be used with calcium injection; 17. It should not be used in combination with acids or bases.

This product is a sterile solution made of deacetylated lanolin and 10% ethanol. Molecular formula: C47H74O19 Molecular weight: 943.09

1. When used together with amphotericin B, corticosteroids or potassium-losing diuretics such as bumetanide (the product is buturamine) and ethacrynic acid (ethacrynic acid), it can cause hypokalemia and lead to digitalis poisoning; 2. When used together with antacids (especially magnesium trisilicate) or antidiarrheal adsorbents such as white clay, pectin, cholestyramine, and other anion exchange resins, sulfasalazine or neomycin, and para-aminosalicylic acid, it can inhibit the absorption of digitalis cardiac glycosides and lead to a weakening of the effect of cardiac glycosides; 3. When used together with antiarrhythmic drugs, calcium salts When injection, cocaine, pancuronium bromide (PancuroniumBromide, Pan Kelong, Bahuolang), rauwolfia alkaloids, succinylcholine (Sceline; SuxamethoniumChloride) or adrenergic drugs are used together, arrhythmias may occur due to additive effects; 4 Digitalized patients with severe or complete atrioventricular block and normal blood potassium should not use potassium salts at the same time, but when thiazide diuretics are used with this product, potassium salts are often required to prevent hypokalemia; 5 β-receptor blockers used with this product may cause severe bradycardia due to atrioventricular block, which should be taken seriously. However, it does not rule out the use of beta-blockers for supraventricular tachyarrhythmias where digitalis cannot control the ventricular rate; 6. When used together with quinidine, the blood concentration of this product can be increased by about one-fold. The degree of increase is related to the dosage of quinidine and can even reach toxic concentrations. Even if digoxin is discontinued, its blood concentration continues to rise. This is because quinidine replaces digoxin from tissue binding and reduces its distribution volume. When the two drugs are used together, the dosage of digoxin should be reduced by 1/2-1/3; 7 When used together with verapamil, diltiazem, and amiodarone, the blood concentration of digoxin can be increased due to the reduction of the renal and systemic clearance rate of digoxin, which can cause severe bradycardia; 8 Spironolactone can prolong the half-life of this product, and the dose or dosing interval needs to be adjusted, and the blood concentration of this product should be followed up and monitored; 9 Angiotensin converting enzyme inhibitors and their receptor antagonists can increase the blood concentration of this product; 10 EdrophoniumChloride (Tensilon) and this product can cause obvious bradycardia when used together; 11 Indomethacin (Indome 12. When used with heparin, the dosage of heparin should be adjusted because this product may partially offset the anticoagulant effect of heparin; 13. When using magnesium sulfate intravenously during digitalization, extreme caution should be exercised, especially when calcium salts are also injected intravenously, as heart block may occur; 14. Erythromycin can increase the absorption of this product in the gastrointestinal tract by changing the gastrointestinal flora; 15. Metoclopramide (Maxolon) reduces the bioavailability of digoxin by about 25% due to promoting intestinal motility. Propane increases the bioavailability of digoxin by about 25% due to inhibiting intestinal peristalsis; 16. It is forbidden to be used with calcium injection; 17. It should not be used in combination with acids or bases.