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Cefathiamidine

Cefathiamidine structure

CAS No:
33075-00-2
Formula:
C19H28N4O6S2
Chemical Name:
Cefathiamidine
Synonyms:
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[(acetyloxy)methyl]-7-[[2-[[[(1-methylethyl)amino][(1-methylethyl)imino]methyl]thio]acetyl]amino]-8-oxo-,(6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[(acetyloxy)methyl]-7-[[[[[(1-methylethyl)amino][(1-methylethyl)imino]methyl]thio]acetyl]amino]-8-oxo-,(6R-trans)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[2-[(N,N′-diisopropylamidino)thio]acetamido]-3-(hydroxymethyl)-8-oxo-,acetate (ester);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[(acetyloxy)methyl]-7-[[[[[(1-methylethyl)amino][(1-methylethyl)imino]methyl]thio]acetyl]amino]-8-oxo-,(6R,7R)-;(6R,7R)-3-[(Acetyloxy)methyl]-7-[[2-[[[(1-methylethyl)amino][(1-methylethyl)imino]methyl]thio]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Cefathiamidine
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

Cefathiamidine is a first-generation cephalosporin antibacterial agent and is used to treat infections caused by susceptible bacteria. Cefathiamidine exhibits a wide spectrum of antimicrobial activity against bacteria. Cefathiamidine is used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis[1][2].

Cefathiamidine Basic Attributes

Molecular Weight：

472.58

Exact Mass：

472.58

Characteristics

PSA：

188

XLogP3：

0.5

Density：

1.5±0.1 g/cm3

Refractive Index：

1.653

Cefathiamidine Use and Manufacturing

Cefathiamidine is an antibacterial agent that exhibits a broad spectrum of bactericidal activity against gram-positive bacteria.

Drug Function and Efficacy

No specific pharmacological information is provided

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Cefathiamidine for injection
Ingredients	The main ingredient of this product is cefathiamidine, and its chemical name is (6R,7R)-3-[(acetyloxy)methyl]-7-[α-(N,N-diisopropylamidinothio)acetylamino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid betaine.
Indication	After intramuscular injection of this product combined with probenecid 1g, the 12-hour urine excretion volume dropped to 65.7% of the administered dose.
Specifications	0.5g
Manufacturer	Hainan Lingkang Pharmaceutical Co., Ltd.

Cefathiamidine for injection
Ingredients	The main ingredient of this product is cefathiamidine, and its chemical name is (6R,7R)-3-[(acetyloxy)methyl]-7-[α-(N,N-diisopropylamidinothio)acetylamino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid betaine.
Indication	After intramuscular injection of this product combined with probenecid 1g, the 12-hour urine excretion volume dropped to 65.7% of the administered dose.
Specifications	1.0g
Manufacturer	Shanxi Zhendong Taisheng Pharmaceutical Co., Ltd.

Cefathiamidine for injection
Ingredients	The main ingredient is: Cefathiamidine, chemical name: (6R, 7R)-3[(acetyloxy)methyl]-7-[-(N, N'-diisopropylamidinothio)-acetylamino]8-oxo-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylic acid betaine.
Indication	After intramuscular injection of this product combined with probenecid 1g, the 12-hour urine excretion volume dropped to 65.7% of the administered dose.
Specifications	0.5 g
Manufacturer	Guangzhou Baiyunshan Pharmaceutical Co., Ltd. Guangzhou Baiyunshan Pharmaceutical General

See More Related Drugs

Registered Holders

Suzhou Wanqing Pharmaceutical Co., Ltd.

China
Active
CSPC Zhongnuo PHARMACEUTICAL(Shijiazhuang) Co., Ltd.

China
Active
Shandong Ruiying Pioneer Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

Recommended Suppliers of Cefathiamidine

Hangzhou Dawn Ray Pharmaceutical Co.,Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP

Cefathiamidine

CAS No.: 33075-00-2

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