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Home > Encyclopedia > Δ2-Cefuroxime Axetil

Δ2-Cefuroxime Axetil

pharmaceutical raw materials
Δ2-Cefuroxime Axetil structure

Δ2-Cefuroxime Axetil 

structure
  • CAS No:

    123458-61-7

  • Formula:

    C20H22N4O10S

  • Chemical Name:

    Δ2-Cefuroxime Axetil

  • Synonyms:

    Δ2-Cefuroxime Axetil;(6R,7R)-3-[[(AMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-furanyl)-2-(MethoxyiMino)acetyl]aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic Acid 1-(Acetyloxy)ethyl Ester;[6R-[6α, 7β(Z)]]-3-[[(Aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid 1-(acetyloxy)ethyl ester;Cefuroxime Axetil EP Impurity A;Cefuroxime Axetil Impurity A (EP)

  • Categories:

    Analytical Chemistry  >  Standard

Δ2-Cefuroxime Axetil Basic Attributes

510.47448

510.105652

JIH1E51JH3

Characteristics

218.84000

2.10

1.61±0.1 g/cm3(Predicted)

1.665

Safety Information

NONH for all modes of transport

Δ2-Cefuroxime Axetil Use and Manufacturing

It is an oral prodrug of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester is applied in therapy as a mixture of the R and S diastereoisomers.

Computed Properties

Molecular Weight:510.5
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:12
Exact Mass:510.10566408
Monoisotopic Mass:510.10566408
Topological Polar Surface Area:214
Heavy Atom Count:35
Complexity:954
Defined Atom Stereocenter Count:2
Undefined Atom Stereocenter Count:2
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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