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dihydromevinolin

dihydromevinolin structure

CAS No:
77517-29-4
Formula:
C24H38O5
Chemical Name:
dihydromevinolin
Synonyms:
dihydromevinolin;(S)-2-Methylbutyric acid [(1S)-1,2,3,4,4a,7,8,8aα-octahydro-3β,7α-dimethyl-8α-[2-[[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran]-2-yl]ethyl]naphthalen]-1β-yl ester;dihydro-lovastatin;Lovastatin Related CoMpound A;Lovastatin Related Compound A (20 mg) (Dihydro-lovastatin);(2S)-2-Methylbutanoic Acid (1S,3S,4aR,7S,8S,8aS)-1,2,3,4,4a,7,8,8a-Octahydro-3,7-diMethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester;4a,5-Dihydro Lovastatin;L 154883
Categories:
Analytical Chemistry > Standard

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Description

White to Off-White Solid

dihydromevinolin Basic Attributes

Molecular Weight：

406.55552

Exact Mass：

406.27192431 g/mol

HScode：

2933997500

Characteristics

PSA：

72.83000

XLogP3：

4.27540

Density：

1.10±0.1 g/cm3(Predicted)

Boiling Point：

534.8ºC at 760 mmHg

Flash Point：

174.5ºC

Refractive Index：

1.52

Drug Information

MeSH：

Compounds that inhibit HYDROXYMETHYLGLUTARYL COA REDUCTASES. They have been shown to directly lower CHOLESTEROL synthesis. (See all compounds classified as Hydroxymethylglutaryl-CoA Reductase Inhibitors.)

MeSH Entry Terms：

4a,5-dihydromevinolin

dihydromevinolin Use and Manufacturing

4a,5-Dihydro Lovastatin is an impurity in Lovastatin (L472225) bulk drug.

Computed Properties

Molecular Weight:406.6
XLogP3:5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:406.27192431
Monoisotopic Mass:406.27192431
Topological Polar Surface Area:72.8
Heavy Atom Count:29
Complexity:614
Defined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes