 Home > Encyclopedia > Coumarin 7

Coumarin 7

Coumarin 7 structure

CAS No:
27425-55-4
Formula:
C20H19N3O2
Chemical Name:
Coumarin 7
Synonyms:
2H-1-Benzopyran-2-one,3-(1H-benzimidazol-2-yl)-7-(diethylamino)-;Coumarin,3-(2-benzimidazolyl)-7-(diethylamino)-;3-(1H-Benzimidazol-2-yl)-7-(diethylamino)-2H-1-benzopyran-2-one;3-(2-Benzimidazolyl)-7-(diethylamino)coumarin;Coumarin 7;Coumarin 535;Oracet Yellow 8GF;C.I. Disperse Yellow 82;Setaron Brilliant Flavine 8GFF;Terasil Brilliant Flavine 8GFF;Disperse Yellow 82;Kayaset Yellow SF-G;K 7;Polycron Brilliant Yellow 10GF;Terasil Flavine 8GFF;Sumikaron Brilliant Flavine S 10G;Disperse Yellow 8GFF;Yellow 8GFF;Solvent Yellow 185;C.I. Solvent Yellow 185;C.I. 551200;Solvent Yellow 145;C.I. Solvent Yellow 145;Keystone Fluorescent Yellow 10G;NSC 303254;3-(Benzimidazol-2-yl)-7-diethylamino-2H-benzopyran-2-one;Day-Glo Savannah Yellow;C.I. Solvent Yellow 171;Fluorescent Yellow 9GF;3-(2′-Benzimidazolyl)-7-(diethylamino)coumarin;D 820 Savannah Yellow;Savannah Yellow;Fluorescent Yellow 10G;136403-01-5;12239-58-6;54576-77-1;222414-02-0
Categories:
Dyes and Pigments > Dye

Request for Quotation

Description

bright yellow powder

Coumarin 7 Basic Attributes

Molecular Weight：

333.38

Exact Mass：

333.38

EC Number：

248-451-4

NSC Number：

303254

DSSTox ID：

DTXSID4067309

HScode：

29332900

Characteristics

PSA：

58.2

XLogP3：

4.18250

Appearance：

Bright yellow Powder

Density：

1.345 g/cm³

Melting Point：

242 °C

Boiling Point：

602.3ºC at 760 mmHg

Flash Point：

318ºC

Refractive Index：

1.692

Storage Conditions：

-20°C

Vapor Pressure：

1.85E-14mmHg at 25°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38-20/21/22

safety instructions：

26-38-37/39

Marks：

Xi,Xn

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H315-H319-H335

GHS Classification：

|Warning|H315 (23.08%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 220 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

coumarin 7

Coumarin 7 Use and Manufacturing

Methods of Manufacturing

Using 4-diethylamino salicylaldehyde and 2-cyanomethylbenzimidazole as raw materials, the two are condensed in DMF solvent to form imine, and then hydrolyzed in acidic medium to obtain the product. Or take 4-diethylamino salicylaldehyde and 2-benzothiazole acetic acid as raw materials and condense the two to obtain the product. After solvent recovery and other post-processing, filtration and drying, the finished product is obtained. Add 8g of 4-diethylaminosalicylic aldehyde, 7.2g of 2-cyanomethylbenzimidazole, and 65ml of dimethylformamide (DMF) into the reaction flask. After the solid is dissolved, add a small amount of morpholine and glacial acetic acid. React at 25°C for 24h. Filter, wash, and dry to obtain intermediate imine (2-imino-3-2-benzimidazole)-7-diethylaminocoumarin. Add 100ml of hydrochloric acid and 5.7g of the above imine to the reaction flask, reflux at 100-103°C for 2.5h, cool to 5°C, add 250g of ice, neutralize with 50% NaOH solution to pH=7.5, precipitate a yellow solid, filter, The product is bright yellow after washing and drying.

Uses

Suitable as laser dye

Manufacturing Info：

2H-1-Benzopyran-2-one, 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-: ACTIVE

Computed Properties

Molecular Weight:333.4
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:333.147726857
Monoisotopic Mass:333.147726857
Topological Polar Surface Area:58.2
Heavy Atom Count:25
Complexity:531
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Phosphorus oxychloride

Ethyl cyanoacetate

Morpholine

Sodium acetate trihydrate

Dimethylformamide

o-Phenylenediamine