H-ACPC-OET HCL
-
H-ACPC-OET HCL
structure -
-
CAS No:
42303-42-4
-
Formula:
C6H12ClNO2
-
Chemical Name:
H-ACPC-OET HCL
-
Synonyms:
Ethyl 1-aminocyclopropane-1-carboxylate hydrochloride;H-AC3C-OEt Hydrochloride;H-ACPC-OET hydrochloride;methyl 1-aminocyclopropanecarboxylate, HCl salt;Ethyl 1-aminocyclopropanecarboxylate hydrochloride≥ 99% (Assay);1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID ETHYL ESTER HCL;ethyle1-aminocyclopropanecarboxylate hydrochloride;1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID ETHYL ESTER HYDROCHLORIDE
- Categories:
-
CAS No:
Characteristics
52.3
1.15300
White Crystalline Powder
gt. 110.0 and le 118.0 °C
159.7ºC at 760 mmHg
33.9ºC
Store at 0°C
Safety Information
NONH for all modes of transport
3
36/37/38-22
26-36-38-36/37-24/25-22-7/9-36/37/39
Xn
P264, P270, P280, P301+P312, P302+P352, P321, P330, P332+P313, P362, P501
H302-H315
|Warning|H302 (97.44%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P302+P352, P321, P330, P332+P313, P362, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
H-ACPC-OET HCL Use and Manufacturing
Thionyl chloride (150 mL, 2.056 mol) was added slowly below 0 °C to a suspension of 1- aminocyclopropanecarboxylic acid (100 g, 0.989 mol) in anhydrous ethanol (1 L). The mixture was stirred at 70 °C for 20 h. TLC (methanol, Thionyl chloride (150 mL, 2.056 mol) was added slowly below 0 °C to a suspension of 1- aminocyclopropanecarboxylic acid (100 g, 0.989 mol) in anhydrous ethanol (1 L). The mixture was stirred at 70 °C for 20 h. TLC (methanol, Rf = 0.4) showed that most of the starting material wasconsumed. Then the solution was concentrated to give 210 g of crude product. The residue was dissolved in water and adjusted to a pH between 9 and 10 with potassium carbonate. The aqueous layer was extracted with dichloromethane (1 L x 3). The combined organic layers were concentrated to dryness. The residue was dissolved in ethyl acetate (300 mL) and hydrochloride in ethyl acetate (250 mL, 4M) was added slowly to the solution below -30°C. It was stirred for 30 mm at 0°C. A solid precipitated and it was filtered under nitrogen atmosphere to give ethyl 1-aminocyclopropanecarboxylate hydrochloride (132 g, 80.6percent yield) as a white solid.The following ‘H-N MR is from the free amine.‘H-NMR (400MHz, chloroform-d, ): 6 [ppm] = 0.91-1.02 (m, 2H), 1.15-1.30 (m, 5H), 2.17 (s, 2H), 4.10 (d, 2H).Thionyl chloride (150 mL, 2.056 mol) was added slowly below 0 °C to a suspension of 1- aminocyclopropanecarboxylic acid (100 g, 0.989 mol) in anhydrous ethanol (1 L). The mixture was stirred at 70 °C for 20 h. TLC (methanol,
Computed Properties
Molecular Weight:165.62
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:165.0556563
Monoisotopic Mass:165.0556563
Topological Polar Surface Area:52.3
Heavy Atom Count:10
Complexity:129
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Recommended Suppliers of H-ACPC-OET HCL
-
![China]()
CN
2 YRS
Business licensedTrader Supplier of pharmaceutical intermediates,excipients,plant extracts,food additives,CDMO,fine cheimcals,Octadecanedioic acid,Eicosanedioic AcidInquiryCAS No.: 42303-42-4Grade: Pharmaceutical GradeContent: 99% -
![China]()
CN
4 YRS
Business licensedTrader Supplier of API OLED Organic intermediateInquiryCAS No.: 42303-42-4Grade: Industrial GradeContent: 98%
Learn More Other Chemicals
-
2,5-DIAMINO-2-METHYL-PENTANOIC ACID HCL
52372-32-4
-
Adrimycin Benzoylhydrazone HCl
66996-52-9
-
(S)-3-AMINO-4,4-DIPHENYL-BUTYRIC ACID HCL
544455-95-0
-
Cerdulatinib HCl salt Formula
1369761-01-2
-
(+)-(1R,2R)-O-DESMETHYL TRAMADOL HCL Formula
148262-77-5
-
BENZYL-D7-AMINE HCL Formula
352431-27-7
-
3-Bromo-N,4-dimethylaniline, HCl Structure
1187386-24-8
-
S(-)-SCH-23388 NOR METHYL- HCL Structure
107128-79-0
-
What is 1-(4-Chlorophenoxy)-2-propanaMine HCl
23471-46-7
-
What is 1-(6-CHLORO-HEXYL)-1H-IMIDAZOLE HCL
869094-62-2