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Home > Encyclopedia > FMOC-LYS(IVDDE)-OH

FMOC-LYS(IVDDE)-OH

FMOC-LYS(IVDDE)-OH structure

FMOC-LYS(IVDDE)-OH 

structure
  • CAS No:

    204777-78-6

  • Formula:

    C34H42N2O6

  • Chemical Name:

    FMOC-LYS(IVDDE)-OH

  • Synonyms:

    Fmoc-Lys(Ddiv)-OH;(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutylamino)hexanoic acid;FMoc-Lys(ivDde)-OH N-α-FMoc-N-ε-1-(4,4-diMethyl-2,6-dioxocyclohex-1 -ylidene)-3-Methylbutyl-L-lysine;FMoc-Lys(Ddiv)-OHFMoc-Ly;Nα-Fmoc-Nε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-lysine≥ 99.9% (HPLC, Chiral purity);Fmoc-Lys(ivDde)-OHNovabiochem;Nalpha-Fmoc-Nepsilon-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-L-lysine;FMOC-N-EPSILON-1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)-3-METHYLBUTYL-L-LYSINE

  • Categories:

    Biochemical Engineering  >  Amino Acids and Derivatives

Description

White to pale yellow powder

FMOC-LYS(IVDDE)-OH Basic Attributes

574.71

574.304260

DTXSID40454104

29242970

Characteristics

122

6.8

White Powder

1.2±0.1 g/cm3

765.6°C at 760 mmHg

416.8±32.9 °C

1.570

2-8°C

0mmHg at 25°C

Safety Information

NONH for all modes of transport

3

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P322, P330, P337+P313, P363, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

FMOC-LYS(IVDDE)-OH Use and Manufacturing

Fmoc-Lys(ivDde)-OH is especially useful for preparing peptides selectively modified on the Lys sidechain, such as peptides labeled peptides, PEGylated peptides or peptides cyclized through the Lys sidechain. The ivDde protective group possesses higher orthogonality regarding Boc and Fmoc in comparison to Dde. The ivDde group can be selectively removed with hydrazine in the presence of acid labile groups such as t-butyl and trityl based protecting groups.

Computed Properties

Molecular Weight:574.7
XLogP3:5.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:13
Exact Mass:574.30428706
Monoisotopic Mass:574.30428706
Topological Polar Surface Area:125
Heavy Atom Count:42
Complexity:1020
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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