2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide
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2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide
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CAS No:
108605-62-5
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Formula:
C12H9F3N2O2
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Chemical Name:
2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide
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Synonyms:
2-Butenamide,2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-;2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide;2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide;2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide;210165-52-9
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CAS No:
2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide Basic Attributes
270.21
270.21
1308068-626-2
L04AA31
Characteristics
73.12000
3.07248
White solid.
1.4±0.1 g/cm3
410.8ºC at 760 mmHg
173.3±27.9 °C
1.552
+2C to +8C
6.63E-06mmHg at 25°C
2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide Use and Manufacturing
The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis.LEF-M interferes with dendritic cell function
Computed Properties
Molecular Weight:270.21
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:270.06161202
Monoisotopic Mass:270.06161202
Topological Polar Surface Area:73.1
Heavy Atom Count:19
Complexity:426
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide
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CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food AdditivesInquiryCAS No.: 108605-62-5Content: 99.00% -
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of fine chemicals,pharmaceutical materialsInquiryCAS No.: 108605-62-5Grade: industrial GradeContent: 98%
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2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide
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