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Home > Encyclopedia > 2-(4-(ACETYLAMINO)-3-NITROPHENYL)PROPIONITRILE

2-(4-(ACETYLAMINO)-3-NITROPHENYL)PROPIONITRILE

2-(4-(ACETYLAMINO)-3-NITROPHENYL)PROPIONITRILE structure

2-(4-(ACETYLAMINO)-3-NITROPHENYL)PROPIONITRILE 

structure
  • CAS No:

    57555-89-2

  • Formula:

    C11H11N3O3

  • Chemical Name:

    2-(4-(ACETYLAMINO)-3-NITROPHENYL)PROPIONITRILE

  • Synonyms:

    2-(4-(ACETYLAMINO)-3-NITROPHENYL)PROPIONITRILE;N-[4-(1-Cyanoethyl)-2-nitrophenyl]acetamide;2-(4-(acetylamino)-3-nitrophenyl)propanitrile;N-[4-(Cyano-methyl-methyl)-2-nitro-phenyl]-acetamide;SCHEMBL4141603;CTK5A7062;DTXSID70481342

2-(4-(ACETYLAMINO)-3-NITROPHENYL)PROPIONITRILE Basic Attributes

233.22334

233.08000

DTXSID70481342

Characteristics

98.7

3.35298

2-(4-(ACETYLAMINO)-3-NITROPHENYL)PROPIONITRILE Use and Manufacturing

Methods of Manufacturing

Methyl benzylacetonitrile with dimethyl sulfate to produce 2-phenylpropionitrile, then nitrate with mixed acid, and obtain 2-(4-acetamidophenyl)propionitrile through reduction and acetylation. The latter is then nitrated with mixed acid to obtain the product.

Uses

Intermediate of flupirprofen.

Computed Properties

Molecular Weight:233.22
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:233.08004122
Monoisotopic Mass:233.08004122
Topological Polar Surface Area:98.7
Heavy Atom Count:17
Complexity:355
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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