aprosulate
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aprosulate
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CAS No:
123072-45-7
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Formula:
C27H34N2O70S16.16Na
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Chemical Name:
aprosulate
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Synonyms:
aprosulate;LW 10082;LW-10082;Aprosulate Sodium;UNII-311154J4LN;311154J4LN;Aprosulate sodium [INN];Aprosulato sodico;Aprosulate sodique;Aprosulatum natricum
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CAS No:
Description
Aprosulate Sodium is the sodium salt form of aprosulate, a synthetic sulfated bis(lactobionic acid amide) derivative and heparin analogue with anticoagulant activity. Aprosulate is made up of two fully sulfated lactobionic acid moieties with a diamine spacer via two amide bonds. This agent inhibits thrombin by antagonizing heparin cofactor II (HCII) and thus blocking thrombin-induced platelet aggregation. It prolongs clotting time.
Drug Information
Agents that prevent BLOOD CLOTTING. (See all compounds classified as Anticoagulants.)|Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN. (See all compounds classified as Fibrinolytic Agents.)
aprosulate
Computed Properties
Molecular Weight:2387.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:70
Rotatable Bond Count:36
Exact Mass:2385.3056697
Monoisotopic Mass:2385.3056697
Topological Polar Surface Area:1290
Heavy Atom Count:131
Complexity:4720
Defined Atom Stereocenter Count:18
Covalently-Bonded Unit Count:17
Compound Is Canonicalized:Yes
- Hot Searches
- tert-butanol
- hexanoate
- dabco
- borane
- iron ii hydroxide
- dichloromethane density
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