Benzoic acid, 2-amino-6-fluoro-3-nitro-, ethyl ester

Ethyl 2-amino-6-fluoro-3-nitrobenzoate (5.0g) was melted in methanol (50 ml), 1.9M sodium methoxide / methanol solution (5 ml) was dropped under churning at 0 degree C, and it agitated at the room temperature for 1 hour. After cooling reaction mixture at 0 degree C and adding 2-N chloride, output was collected and the notation compound (5.43g) was obtained by washing with water.To a stirred solution of To a stirred solution of To a stirred solution of To a stirred solution of C. Synthesis of benzimidazole ester F-20: 5-Fluoro-2-[[[(4-methoxy-2, 6-dimethyl- phenyl)sulfonyl]-methyl-amino]-methyl]-3H-benzoimidazole-4-carboxylic acid methyl ester (F-20); (I) A solution of Example 27; 2- (2, 3-Dichloro-phenylamino)-5-fluoro-3H-benzoimidazole-4-carboxylic acid; (a) 2, 3-Diamino-6-fluoro-benzoic acid ethyl ester; Commercially available

Molecular Weight:228.18
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:228.05463493
Monoisotopic Mass:228.05463493
Topological Polar Surface Area:98.1
Heavy Atom Count:16
Complexity:281
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes