Bunaftine
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Bunaftine
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CAS No:
32421-46-8
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Formula:
C21H30N2O
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Chemical Name:
Bunaftine
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Synonyms:
1-Naphthalenecarboxamide,N-butyl-N-[2-(diethylamino)ethyl]-;1-Naphthamide,N-butyl-N-[2-(diethylamino)ethyl]-;N-Butyl-N-[2-(diethylamino)ethyl]-1-naphthalenecarboxamide;Bunaphtide;Bunaftide;Bunaftine;Meregon
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CAS No:
Description
Bunaftide (Bunaftine; Bunaphtide; Meregon) is an antiarrhythmic agent.
Bunaftine is a naphthalenecarboxamide.|N-Butyl-N-(2-(diethylamino)ethyl)-1-naphthamide. A proposed antiarrhythmic that prolongs myocardial refractory period and stabilizes cell membranes.
Bunaftine Basic Attributes
326.484
326.48
251-027-1
GH09PRQ3FU
DTXSID90186165
C - Cardiovascular system
2924299090
Characteristics
23.6
4.42390
1.026g/cm3
178 °C
192ºC
1.562
LD50 i.p. in mice: 122 mg/kg (Giannini et al.)
Drug Information
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)
Bunaftide